FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2119318470> ?p ?o ?g. }

• W2119318470 endingPage "3400" @default.
• W2119318470 startingPage "3392" @default.
• W2119318470 abstract "Given the numerous reparative roles glia may play after spinal cord injury (SCI), glial proliferation and cell number were examined in a model of traumatic SCI. Emphasis was placed on analysis of oligodendrocytes and NG2-positive (NG2+) cells, an endogenous cell population that may be involved in oligodendrocyte replacement. Overall, proliferation (assessed by bromodeoxyuridine incorporation) was markedly elevated during the first 2 weeks after injury and declined thereafter; a large portion of these dividing cells likely consisted of microglia-macrophages. Although the total number of NG2+ cells in the epicenter was reduced by half, we noted protracted proliferation in surviving NG2+ cells, with values sevenfold greater than in uninjured controls. Elevated proliferation of NG2+ cells persisted throughout the first 4 weeks after injury. However, the absolute number of NG2+ cells was not increased over controls, suggesting that the daughter cells either did not survive or they differentiated into other cell types. As expected, oligodendrocyte numbers were drastically altered after SCI. By 7 d after injury, the number of oligodendrocytes at the impact site was reduced by 93%. Despite ongoing tissue loss, the number of oligodendrocytes in spared tissue rose threefold at 14 d after injury. Although the function of NG2+ cells within the spinal cord is not completely understood, several studies suggest that they may differentiate into oligodendrocytes. Thus, proliferating NG2+ cells may contribute to the increased oligodendrocyte number observed at 2 weeks after injury. Future studies are required, however, to definitively determine the role NG2+ cells play in oligodendrocyte genesis, remyelination, and other post-injury events." @default.
• W2119318470 created "2016-06-24" @default.
• W2119318470 creator A5023037940 @default.
• W2119318470 creator A5028242629 @default.
• W2119318470 creator A5041415357 @default.
• W2119318470 date "2001-05-15" @default.
• W2119318470 modified "2023-10-13" @default.
• W2119318470 title "Proliferation of NG2-Positive Cells and Altered Oligodendrocyte Numbers in the Contused Rat Spinal Cord" @default.
• W2119318470 cites W1484682139 @default.
• W2119318470 cites W1498285527 @default.
• W2119318470 cites W1529537509 @default.
• W2119318470 cites W176961942 @default.
• W2119318470 cites W1907724378 @default.
• W2119318470 cites W1921871464 @default.
• W2119318470 cites W1965375858 @default.
• W2119318470 cites W1966708171 @default.
• W2119318470 cites W1971675257 @default.
• W2119318470 cites W1973106753 @default.
• W2119318470 cites W1982598770 @default.
• W2119318470 cites W1984352889 @default.
• W2119318470 cites W1989501592 @default.
• W2119318470 cites W1991815902 @default.
• W2119318470 cites W1993335728 @default.
• W2119318470 cites W1994179197 @default.
• W2119318470 cites W2006312185 @default.
• W2119318470 cites W2010075128 @default.
• W2119318470 cites W2013152746 @default.
• W2119318470 cites W2022029245 @default.
• W2119318470 cites W2023080395 @default.
• W2119318470 cites W2023105628 @default.
• W2119318470 cites W2031754120 @default.
• W2119318470 cites W2033322963 @default.
• W2119318470 cites W2041246766 @default.
• W2119318470 cites W2049212652 @default.
• W2119318470 cites W2053846609 @default.
• W2119318470 cites W2057866248 @default.
• W2119318470 cites W2059028717 @default.
• W2119318470 cites W2059352117 @default.
• W2119318470 cites W2065809502 @default.
• W2119318470 cites W2074711277 @default.
• W2119318470 cites W2074924223 @default.
• W2119318470 cites W2076540617 @default.
• W2119318470 cites W2080534886 @default.
• W2119318470 cites W2081422930 @default.
• W2119318470 cites W2082178383 @default.
• W2119318470 cites W2084324436 @default.
• W2119318470 cites W2084853983 @default.
• W2119318470 cites W2093595917 @default.
• W2119318470 cites W2093738970 @default.
• W2119318470 cites W2096262211 @default.
• W2119318470 cites W2098589841 @default.
• W2119318470 cites W2113964043 @default.
• W2119318470 cites W2126362648 @default.
• W2119318470 cites W2126391120 @default.
• W2119318470 cites W2133887238 @default.
• W2119318470 cites W2142835446 @default.
• W2119318470 cites W2144762351 @default.
• W2119318470 cites W2147149841 @default.
• W2119318470 cites W2170645579 @default.
• W2119318470 cites W2400049961 @default.
• W2119318470 cites W3355293 @default.
• W2119318470 doi "https://doi.org/10.1523/jneurosci.21-10-03392.2001" @default.
• W2119318470 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6762495" @default.
• W2119318470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11331369" @default.
• W2119318470 hasPublicationYear "2001" @default.
• W2119318470 type Work @default.
• W2119318470 sameAs 2119318470 @default.
• W2119318470 citedByCount "394" @default.
• W2119318470 countsByYear W21193184702012 @default.
• W2119318470 countsByYear W21193184702013 @default.
• W2119318470 countsByYear W21193184702014 @default.
• W2119318470 countsByYear W21193184702015 @default.
• W2119318470 countsByYear W21193184702016 @default.
• W2119318470 countsByYear W21193184702017 @default.
• W2119318470 countsByYear W21193184702018 @default.
• W2119318470 countsByYear W21193184702019 @default.
• W2119318470 countsByYear W21193184702020 @default.
• W2119318470 countsByYear W21193184702021 @default.
• W2119318470 countsByYear W21193184702022 @default.
• W2119318470 countsByYear W21193184702023 @default.
• W2119318470 crossrefType "journal-article" @default.
• W2119318470 hasAuthorship W2119318470A5023037940 @default.
• W2119318470 hasAuthorship W2119318470A5028242629 @default.
• W2119318470 hasAuthorship W2119318470A5041415357 @default.
• W2119318470 hasBestOaLocation W21193184701 @default.
• W2119318470 hasConcept C124964019 @default.
• W2119318470 hasConcept C1491633281 @default.
• W2119318470 hasConcept C169760540 @default.
• W2119318470 hasConcept C203014093 @default.
• W2119318470 hasConcept C204232928 @default.
• W2119318470 hasConcept C2776914184 @default.
• W2119318470 hasConcept C2776985911 @default.
• W2119318470 hasConcept C2777619251 @default.
• W2119318470 hasConcept C2778260397 @default.
• W2119318470 hasConcept C2778334475 @default.
• W2119318470 hasConcept C2778609137 @default.
• W2119318470 hasConcept C2779830541 @default.
• W2119318470 hasConcept C2780775167 @default.

• next