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- W2119352783 abstract "The chemokine macrophage inflammatory protein 1beta/CCL4, ligand of the major HIV co-receptor CCR5, is encoded by two genes, Act-2 and Lag-1. Our work focused on R22H, a variant of Lag-1 located near the N-loop, in the 310 turn, a domain essential for interacting with CCR5. We observed that HIV-1-infected patients from the SEROCO cohort, bearing the R22H variant either at the homozygous or heterozygous state, exhibit a worse global survival compared with wild-type homozygous individuals." @default.
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- W2119352783 date "2005-05-20" @default.
- W2119352783 modified "2023-09-27" @default.
- W2119352783 title "Influence of the R22H variant of macrophage inflammatory protein 1β/Lag-1 in HIV-1 survival" @default.
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- W2119352783 doi "https://doi.org/10.1097/01.aids.0000168979.97584.18" @default.
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