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- W2119470334 abstract "The aim of this study was to investigate whether exposure to a range of relatively low concentrations of aged secondhand smoke (SHS), similar to those encountered commonly in the community, would impair endothelial function in a concentration-dependent manner. Exposure to SHS impairs endothelial function in humans. The concentration-dependent relationship for aged SHS effects on endothelial function after an exposure of short duration is unknown. Thirty-three healthy nonsmokers were exposed to 1 of 2 low levels of aged SHS or to conditioned filtered air for 30 min. The primary end point was change in maximal percent brachial artery flow-mediated dilation after exposure. In a linear regression model for each increase in SHS exposure by 100 μg/m3 respirable suspended particles, the absolute maximal percent brachial artery flow-mediated dilation was reduced by 0.67%. We did not find evidence of a threshold for the effect of SHS on flow-mediated dilation. Short-term exposure to real-world levels of aged SHS for 30 min resulted in a concentration-dependent decrease in endothelial function as measured by flow-mediated dilation." @default.
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- W2119470334 date "2012-05-01" @default.
- W2119470334 modified "2023-10-03" @default.
- W2119470334 title "The Exposure-Dependent Effects of Aged Secondhand Smoke on Endothelial Function" @default.
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- W2119470334 doi "https://doi.org/10.1016/j.jacc.2012.02.025" @default.
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