FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2119691340> ?p ?o ?g. }

• W2119691340 endingPage "323" @default.
• W2119691340 startingPage "315" @default.
• W2119691340 abstract "Identification of long tracts responsible for the initiation of spontaneous locomotion is critical for spinal cord injury (SCI) repair strategies. Pathways derived from the mesencephalic locomotor region and pontomedullary medial reticular formation responsible for fictive locomotion in decerebrate preparations project to the thoracolumbar levels of the spinal cord via reticulospinal axons in the ventrolateral funiculus (VLF). However, white matter regions critical for spontaneous over-ground locomotion remain unclear because cats, monkeys, and humans display varying degrees of locomotor recovery after ventral SCIs. We studied the contributions of myelinated tracts in the VLF and ventral columns (VC) to spontaneous over-ground locomotion in the adult rat using demyelinating lesions. Animals received ethidium bromide plus photon irradiation producing discrete demyelinating lesions sufficient to stop axonal conduction in the VLF, VC, VLF–VC, or complete ventral white matter (CV). Behavior [open-field Basso, Beattie, and Bresnahan (BBB) scores and grid walking] and transcranial magnetic motor-evoked potentials (tcMMEP) were studied at 1, 2, and 4 weeks after lesion. VLF lesions resulted in complete loss or severe attenuation of tcMMEPs, with mean BBB scores of 18.0, and no grid walking deficits. VC lesions produced behavior similar to VLF-lesioned animals but did not significantly affect tcMMEPs. VC–VLF and CV lesions resulted in complete loss of tcMMEP signals with mean BBB scores of 12.7 and 6.5, respectively. Our data support a diffuse arrangement of axons within the ventral white matter that may comprise a system of multiple descending pathways subserving spontaneous over-ground locomotion in the intact animal." @default.
• W2119691340 created "2016-06-24" @default.
• W2119691340 creator A5011792461 @default.
• W2119691340 creator A5015817902 @default.
• W2119691340 creator A5021421301 @default.
• W2119691340 creator A5033936414 @default.
• W2119691340 creator A5047319320 @default.
• W2119691340 creator A5051095641 @default.
• W2119691340 creator A5051267214 @default.
• W2119691340 creator A5074613686 @default.
• W2119691340 creator A5079136793 @default.
• W2119691340 creator A5090876424 @default.
• W2119691340 date "2002-01-01" @default.
• W2119691340 modified "2023-10-11" @default.
• W2119691340 title "Functional Redundancy of Ventral Spinal Locomotor Pathways" @default.
• W2119691340 cites W1184938141 @default.
• W2119691340 cites W1514813533 @default.
• W2119691340 cites W1581736410 @default.
• W2119691340 cites W1593318003 @default.
• W2119691340 cites W1599591504 @default.
• W2119691340 cites W185036824 @default.
• W2119691340 cites W1948129507 @default.
• W2119691340 cites W1963537677 @default.
• W2119691340 cites W1973915905 @default.
• W2119691340 cites W1975724680 @default.
• W2119691340 cites W1982990058 @default.
• W2119691340 cites W1984352889 @default.
• W2119691340 cites W1985075855 @default.
• W2119691340 cites W1996521547 @default.
• W2119691340 cites W2003440016 @default.
• W2119691340 cites W2005466397 @default.
• W2119691340 cites W2007011774 @default.
• W2119691340 cites W2008116710 @default.
• W2119691340 cites W2009740879 @default.
• W2119691340 cites W2017599428 @default.
• W2119691340 cites W2031295712 @default.
• W2119691340 cites W2035452858 @default.
• W2119691340 cites W2047038232 @default.
• W2119691340 cites W2053698168 @default.
• W2119691340 cites W2057950111 @default.
• W2119691340 cites W2064521578 @default.
• W2119691340 cites W2080346261 @default.
• W2119691340 cites W2095276281 @default.
• W2119691340 cites W2144428460 @default.
• W2119691340 cites W2170645579 @default.
• W2119691340 cites W2170962986 @default.
• W2119691340 cites W2171343059 @default.
• W2119691340 cites W2209268503 @default.
• W2119691340 cites W2258205771 @default.
• W2119691340 cites W2337325908 @default.
• W2119691340 cites W2395829014 @default.
• W2119691340 cites W2396436740 @default.
• W2119691340 cites W2396664573 @default.
• W2119691340 cites W2399491767 @default.
• W2119691340 cites W2399631956 @default.
• W2119691340 cites W2406741300 @default.
• W2119691340 cites W2410196415 @default.
• W2119691340 cites W2411120243 @default.
• W2119691340 cites W2419433731 @default.
• W2119691340 cites W2432520023 @default.
• W2119691340 doi "https://doi.org/10.1523/jneurosci.22-01-00315.2002" @default.
• W2119691340 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6757623" @default.
• W2119691340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11756515" @default.
• W2119691340 hasPublicationYear "2002" @default.
• W2119691340 type Work @default.
• W2119691340 sameAs 2119691340 @default.
• W2119691340 citedByCount "143" @default.
• W2119691340 countsByYear W21196913402012 @default.
• W2119691340 countsByYear W21196913402013 @default.
• W2119691340 countsByYear W21196913402014 @default.
• W2119691340 countsByYear W21196913402015 @default.
• W2119691340 countsByYear W21196913402016 @default.
• W2119691340 countsByYear W21196913402017 @default.
• W2119691340 countsByYear W21196913402018 @default.
• W2119691340 countsByYear W21196913402019 @default.
• W2119691340 countsByYear W21196913402020 @default.
• W2119691340 countsByYear W21196913402021 @default.
• W2119691340 countsByYear W21196913402022 @default.
• W2119691340 countsByYear W21196913402023 @default.
• W2119691340 crossrefType "journal-article" @default.
• W2119691340 hasAuthorship W2119691340A5011792461 @default.
• W2119691340 hasAuthorship W2119691340A5015817902 @default.
• W2119691340 hasAuthorship W2119691340A5021421301 @default.
• W2119691340 hasAuthorship W2119691340A5033936414 @default.
• W2119691340 hasAuthorship W2119691340A5047319320 @default.
• W2119691340 hasAuthorship W2119691340A5051095641 @default.
• W2119691340 hasAuthorship W2119691340A5051267214 @default.
• W2119691340 hasAuthorship W2119691340A5074613686 @default.
• W2119691340 hasAuthorship W2119691340A5079136793 @default.
• W2119691340 hasAuthorship W2119691340A5090876424 @default.
• W2119691340 hasBestOaLocation W21196913401 @default.
• W2119691340 hasConcept C105702510 @default.
• W2119691340 hasConcept C126838900 @default.
• W2119691340 hasConcept C142724271 @default.
• W2119691340 hasConcept C143409427 @default.
• W2119691340 hasConcept C169760540 @default.
• W2119691340 hasConcept C2776486484 @default.
• W2119691340 hasConcept C2778655484 @default.

• next