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- W2119862644 abstract "The human auditory cortex codes speech temporally according to sequential acoustico-phonetic cues like the voice onset time (VOT). This coding is predominantly left-lateralized in normal readers. We examined VOT-processing asymmetries in adults with a history of developmental dyslexia (DD-history+).Auditory-evoked potentials (AEPs) to voiced (/ba/) and voiceless (/pa/) speech stimuli were recorded from 10 DD-history+ adults and 8 controls. Source modelling of the release component (RC: approximately 240 ms; time-locked to voiced consonantal release and considered reflective of VOT-processing) was conducted to explore VOT asymmetries.Controls demonstrated L>R RC source probe amplitude asymmetry in the auditory cortex. DD-history+ subjects with little persistent reading deficit (n=5) demonstrated normal temporal coding but rightward asymmetry. DD-history+ subjects with severe persistent deficits (n=5) exhibited numerous supplemental AEP components (notably left hemispheric) and inconsistent asymmetry (leftward or alternating).These preliminary findings suggest that DD-history+ adults process auditory speech cues differently than adults without previous DD. The nature of this processing may relate to the severity of persistent reading deficits.Previous dyslexics with little persistent deficit can exhibit atypical functional asymmetry with normal auditory temporal coding. Source modelling represents an effective, non-invasive means of exploring processing asymmetries in clinical populations." @default.
- W2119862644 created "2016-06-24" @default.
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- W2119862644 date "2008-07-01" @default.
- W2119862644 modified "2023-09-27" @default.
- W2119862644 title "Asymmetry of voice onset time-processing in adult developmental dyslexics" @default.
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- W2119862644 doi "https://doi.org/10.1016/j.clinph.2008.02.017" @default.
- W2119862644 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18456549" @default.
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