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- W2119883020 abstract "Abstract Growth patterns in early life are associated with later health. The effect of nutrition during in utero development on later body composition is unclear. We evaluated whether prenatal early invitation to food and/or multiple micronutrient supplementation ( MMS ) in pregnancy has an effect on offspring body composition at 54 months of age. In M aternal and I nfant N utrition I nterventions in M atlab trial ( ISRCTN 16581394) in B angladesh, 4436 pregnant women were randomised into six equally sized groups: double‐masked supplementation with capsules of either 30 mg F e and 400 μ g folic acid, or 60 mg F e and 400 μ g folic acid, or MMS (15 micronutrients), was combined with a randomised early invitation (around 9 weeks) or a usual invitation (around 20 weeks) to start food supplementation (608 kcal 6 days per week). At 54 months, the body composition of the offspring was assessed by leg‐to‐leg bioelectrical impedance analysis. Of the 3267 live singletons with birth anthropometry, 2290 children were measured at 54 months, representing 70% of the live births. There was no interaction between the food and micronutrient supplementation on body composition outcomes. There were no significant differences in a range of anthropometric and body composition measurements, including weight, height, mid‐upper arm circumference, head circumference, skinfold thickness, and fat mass and fat‐free mass between the different prenatal food and micronutrient groups using an intention‐to‐treat analysis. This analysis shows that early invitation to food supplementation and MMS provided to rural B angladeshi women during pregnancy did not affect offspring body composition at 54 months of age." @default.
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- W2119883020 date "2012-12-13" @default.
- W2119883020 modified "2023-10-10" @default.
- W2119883020 title "Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh" @default.
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- W2119883020 doi "https://doi.org/10.1111/mcn.12021" @default.
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