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- W2119986104 abstract "We report here a supramolecular strategy to directly assemble the small molecular antipsychotic drug chlorpromazine (CPZ) into nanostructures, induced by p-sulfonatocalix[4]arene (SC4A) and p-sulfonatocalix[4]arene tetraheptyl ether (SC4AH), with high drug loading efficiencies of 61% and 46%, respectively. The binary host-guest assembly process was monitored using optical transmittance measurements, and the size and morphology of these two kinds of supra-amphiphilic assemblies were identified using a combination of light scattering and high-resolution transmission electron microscopy, which showed solid spherical micelles. This strategy presents new opportunities for the development of high loading drug-containing carriers with easy processability for drug delivery." @default.
- W2119986104 created "2016-06-24" @default.
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- W2119986104 creator A5047225525 @default.
- W2119986104 creator A5059884300 @default.
- W2119986104 creator A5062966442 @default.
- W2119986104 date "2013-12-11" @default.
- W2119986104 modified "2023-10-18" @default.
- W2119986104 title "Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine" @default.
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- W2119986104 doi "https://doi.org/10.1039/c3sm52866a" @default.
- W2119986104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24652226" @default.
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