Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120054312> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2120054312 endingPage "1644" @default.
- W2120054312 startingPage "1637" @default.
- W2120054312 abstract "Assessment of the direct anticryptococcal activity of murine lymphocytes from both Cryptococcus neoformans-immunized and control mice was the focus of this investigation. We demonstrate that at a 2:1 effector cell-to-cryptococcal target cell ratio, effector cell populations comprised of alpha beta T-cell receptor-positive T lymphocytes (98 to 99% CD3+) from C. neoformans-immunized mice inhibited the growth of cryptococcal cells better than similar populations of lymphocytes from nonimmunized control mice. Almost immediately after mixing of cryptococci with the effector cells, C. neoformans-lymphocyte conjugates were observed. The percentage of conjugates increased over the first 30 min of incubation and then remained constant over the next 1.5 h. T-lymphocyte-enriched populations from C. neoformans-immunized mice formed significantly greater percentages of conjugates with cryptococci than control T lymphocytes at each time period that assessment was made. For growth inhibition to occur, direct contact between the effector and target cells was necessary, as evidenced by abrogation of cryptococcal growth inhibition when lymphocyte and cryptococcal cell populations were separated by a porous membrane during the growth inhibition assay. Vital staining of cryptococci after incubation with the T-cell-enriched populations showed that the T lymphocytes killed the cryptococcal cells." @default.
- W2120054312 created "2016-06-24" @default.
- W2120054312 creator A5032662980 @default.
- W2120054312 creator A5078160485 @default.
- W2120054312 date "1995-05-01" @default.
- W2120054312 modified "2023-09-27" @default.
- W2120054312 title "Direct anticryptococcal activity of lymphocytes from Cryptococcus neoformans-immunized mice" @default.
- W2120054312 cites W1527883887 @default.
- W2120054312 cites W1556867369 @default.
- W2120054312 cites W1827119220 @default.
- W2120054312 cites W1877262861 @default.
- W2120054312 cites W1941730708 @default.
- W2120054312 cites W1944918200 @default.
- W2120054312 cites W1944932482 @default.
- W2120054312 cites W1964471774 @default.
- W2120054312 cites W1980562241 @default.
- W2120054312 cites W1986403475 @default.
- W2120054312 cites W2039823714 @default.
- W2120054312 cites W2081066719 @default.
- W2120054312 cites W2083044599 @default.
- W2120054312 cites W2084093106 @default.
- W2120054312 cites W2088188117 @default.
- W2120054312 cites W2097858152 @default.
- W2120054312 cites W2104912668 @default.
- W2120054312 cites W2105909174 @default.
- W2120054312 cites W2113761665 @default.
- W2120054312 cites W2130298734 @default.
- W2120054312 cites W2131747421 @default.
- W2120054312 cites W2133931936 @default.
- W2120054312 cites W2138147795 @default.
- W2120054312 cites W2143616661 @default.
- W2120054312 cites W2145734455 @default.
- W2120054312 cites W2149856975 @default.
- W2120054312 cites W2150547274 @default.
- W2120054312 cites W2181179425 @default.
- W2120054312 cites W2313270174 @default.
- W2120054312 cites W2315224357 @default.
- W2120054312 cites W2332324963 @default.
- W2120054312 cites W4255754038 @default.
- W2120054312 cites W2082175797 @default.
- W2120054312 doi "https://doi.org/10.1128/iai.63.5.1637-1644.1995" @default.
- W2120054312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/173203" @default.
- W2120054312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7729867" @default.
- W2120054312 hasPublicationYear "1995" @default.
- W2120054312 type Work @default.
- W2120054312 sameAs 2120054312 @default.
- W2120054312 citedByCount "23" @default.
- W2120054312 countsByYear W21200543122012 @default.
- W2120054312 countsByYear W21200543122014 @default.
- W2120054312 countsByYear W21200543122022 @default.
- W2120054312 countsByYear W21200543122023 @default.
- W2120054312 crossrefType "journal-article" @default.
- W2120054312 hasAuthorship W2120054312A5032662980 @default.
- W2120054312 hasAuthorship W2120054312A5078160485 @default.
- W2120054312 hasBestOaLocation W21200543121 @default.
- W2120054312 hasConcept C147483822 @default.
- W2120054312 hasConcept C153911025 @default.
- W2120054312 hasConcept C203014093 @default.
- W2120054312 hasConcept C2777761686 @default.
- W2120054312 hasConcept C2777893358 @default.
- W2120054312 hasConcept C2778952914 @default.
- W2120054312 hasConcept C2779413141 @default.
- W2120054312 hasConcept C2992881475 @default.
- W2120054312 hasConcept C51785407 @default.
- W2120054312 hasConcept C86803240 @default.
- W2120054312 hasConcept C89423630 @default.
- W2120054312 hasConceptScore W2120054312C147483822 @default.
- W2120054312 hasConceptScore W2120054312C153911025 @default.
- W2120054312 hasConceptScore W2120054312C203014093 @default.
- W2120054312 hasConceptScore W2120054312C2777761686 @default.
- W2120054312 hasConceptScore W2120054312C2777893358 @default.
- W2120054312 hasConceptScore W2120054312C2778952914 @default.
- W2120054312 hasConceptScore W2120054312C2779413141 @default.
- W2120054312 hasConceptScore W2120054312C2992881475 @default.
- W2120054312 hasConceptScore W2120054312C51785407 @default.
- W2120054312 hasConceptScore W2120054312C86803240 @default.
- W2120054312 hasConceptScore W2120054312C89423630 @default.
- W2120054312 hasIssue "5" @default.
- W2120054312 hasLocation W21200543121 @default.
- W2120054312 hasLocation W21200543122 @default.
- W2120054312 hasLocation W21200543123 @default.
- W2120054312 hasOpenAccess W2120054312 @default.
- W2120054312 hasPrimaryLocation W21200543121 @default.
- W2120054312 hasRelatedWork W1817460788 @default.
- W2120054312 hasRelatedWork W1827538635 @default.
- W2120054312 hasRelatedWork W1959967360 @default.
- W2120054312 hasRelatedWork W2114534320 @default.
- W2120054312 hasRelatedWork W2120054312 @default.
- W2120054312 hasRelatedWork W2322049042 @default.
- W2120054312 hasRelatedWork W2401261051 @default.
- W2120054312 hasRelatedWork W2609326071 @default.
- W2120054312 hasRelatedWork W2912010737 @default.
- W2120054312 hasRelatedWork W3007554449 @default.
- W2120054312 hasVolume "63" @default.
- W2120054312 isParatext "false" @default.
- W2120054312 isRetracted "false" @default.
- W2120054312 magId "2120054312" @default.
- W2120054312 workType "article" @default.