Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120080334> ?p ?o ?g. }
- W2120080334 endingPage "1173" @default.
- W2120080334 startingPage "1165" @default.
- W2120080334 abstract "Overactive bladder and urgency incontinence are common and distressing conditions in older people, for which the first-line pharmacological treatment is a bladder antimuscarinic agent. Of these, oxybutynin is often recommended in guidelines, but is associated with a higher incidence of adverse drug effects, and in particular has been suggested to have deleterious cognitive effects. Despite this, guidelines often suggest oxybutynin as first-line treatment, and insurance based healthcare systems often require oxybutynin to be used as a first-line therapy and fail before reimbursement for the cost of newer anticholinergics is authorised. We reviewed the literature of bladder antimuscarinics in older adults, using the headings overactive bladder, urinary frequency, urgency, urge, oxybutynin, antimuscarinic, older, older people, and frail. In general, oxybutynin had a similar efficacy to other anticholinergic drugs, but a higher incidence of adverse drug events, in particular significant yet unnoticed cognitive impairment. We conclude that oxybutynin should not be used in frail older people." @default.
- W2120080334 created "2016-06-24" @default.
- W2120080334 creator A5008443279 @default.
- W2120080334 creator A5027682118 @default.
- W2120080334 creator A5031133453 @default.
- W2120080334 creator A5037695450 @default.
- W2120080334 creator A5047530781 @default.
- W2120080334 creator A5065077444 @default.
- W2120080334 creator A5086604324 @default.
- W2120080334 creator A5086640818 @default.
- W2120080334 date "2014-09-01" @default.
- W2120080334 modified "2023-10-04" @default.
- W2120080334 title "Are we shortchanging frail older people when it comes to the pharmacological treatment of urgency urinary incontinence?" @default.
- W2120080334 cites W1410775549 @default.
- W2120080334 cites W1485144880 @default.
- W2120080334 cites W1522823251 @default.
- W2120080334 cites W1556806690 @default.
- W2120080334 cites W1558658318 @default.
- W2120080334 cites W1559663349 @default.
- W2120080334 cites W1561545570 @default.
- W2120080334 cites W1571302831 @default.
- W2120080334 cites W1572722564 @default.
- W2120080334 cites W1578634963 @default.
- W2120080334 cites W1600148322 @default.
- W2120080334 cites W1611456680 @default.
- W2120080334 cites W1772646200 @default.
- W2120080334 cites W1821426726 @default.
- W2120080334 cites W1924589945 @default.
- W2120080334 cites W1965162551 @default.
- W2120080334 cites W1965464258 @default.
- W2120080334 cites W1967312126 @default.
- W2120080334 cites W1967347194 @default.
- W2120080334 cites W1969740456 @default.
- W2120080334 cites W1974465804 @default.
- W2120080334 cites W1974750457 @default.
- W2120080334 cites W1975485647 @default.
- W2120080334 cites W1976456240 @default.
- W2120080334 cites W1980249609 @default.
- W2120080334 cites W1981379267 @default.
- W2120080334 cites W1983922691 @default.
- W2120080334 cites W1986053715 @default.
- W2120080334 cites W1993235173 @default.
- W2120080334 cites W1995084523 @default.
- W2120080334 cites W1996684801 @default.
- W2120080334 cites W2008545228 @default.
- W2120080334 cites W2010109877 @default.
- W2120080334 cites W2012897345 @default.
- W2120080334 cites W2017829997 @default.
- W2120080334 cites W2020081435 @default.
- W2120080334 cites W2020594337 @default.
- W2120080334 cites W2024975356 @default.
- W2120080334 cites W2028811068 @default.
- W2120080334 cites W2030052255 @default.
- W2120080334 cites W2037706235 @default.
- W2120080334 cites W2039602892 @default.
- W2120080334 cites W2042189800 @default.
- W2120080334 cites W2044322882 @default.
- W2120080334 cites W2046804170 @default.
- W2120080334 cites W2047813378 @default.
- W2120080334 cites W2056717611 @default.
- W2120080334 cites W2056759810 @default.
- W2120080334 cites W2063975302 @default.
- W2120080334 cites W2067331159 @default.
- W2120080334 cites W2067924801 @default.
- W2120080334 cites W2071967324 @default.
- W2120080334 cites W2072187682 @default.
- W2120080334 cites W2073754334 @default.
- W2120080334 cites W2080571933 @default.
- W2120080334 cites W2081806057 @default.
- W2120080334 cites W2083580221 @default.
- W2120080334 cites W2098192050 @default.
- W2120080334 cites W2100949479 @default.
- W2120080334 cites W2105831905 @default.
- W2120080334 cites W2109858998 @default.
- W2120080334 cites W2113525252 @default.
- W2120080334 cites W2136548062 @default.
- W2120080334 cites W2140757158 @default.
- W2120080334 cites W2141823090 @default.
- W2120080334 cites W2148524234 @default.
- W2120080334 cites W2164059021 @default.
- W2120080334 cites W2164186760 @default.
- W2120080334 cites W2170633057 @default.
- W2120080334 cites W2170644546 @default.
- W2120080334 cites W2230684884 @default.
- W2120080334 cites W2257575319 @default.
- W2120080334 cites W2272230431 @default.
- W2120080334 cites W4247900695 @default.
- W2120080334 doi "https://doi.org/10.1111/ijcp.12447" @default.
- W2120080334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25196247" @default.
- W2120080334 hasPublicationYear "2014" @default.
- W2120080334 type Work @default.
- W2120080334 sameAs 2120080334 @default.
- W2120080334 citedByCount "11" @default.
- W2120080334 countsByYear W21200803342015 @default.
- W2120080334 countsByYear W21200803342016 @default.
- W2120080334 countsByYear W21200803342017 @default.
- W2120080334 countsByYear W21200803342018 @default.
- W2120080334 countsByYear W21200803342020 @default.