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- W2120085812 abstract "Abstract The National Cooperative Gallstone Study (NCGS), funded by the National Institute of Arthritis, Metabolism and Digestive Diseases of the National Institutes of Health, evaluated dietary supplementation with a natural bile acid (chenodiol) for the dissolution of cholesterol gallstones. Since the compound occurred naturally, there was no industrial sponsor. Thus, the study group also conducted preliminary studies of animal toxicology and hepatic morphology, among others, in addition to a randomized, double‐masked, long‐term, multiple‐dose, Phase III clinical trial. The study employed central units for the evaluation of all outcomes with rigorous quality assurance procedures. The study results, study issues, and statistical considerations are described." @default.
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- W2120085812 date "2008-06-13" @default.
- W2120085812 modified "2023-10-17" @default.
- W2120085812 title "National Cooperative Gallstone Study" @default.
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- W2120085812 doi "https://doi.org/10.1002/9780471462422.eoct623" @default.
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