FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120190485> ?p ?o ?g. }

• W2120190485 endingPage "415" @default.
• W2120190485 startingPage "408" @default.
• W2120190485 abstract "Besides melanoma susceptibility genes and shared environmental exposures, part of the familial clustering of cutaneous malignant melanoma (CMM) might be due to familial aggregation of melanoma-associated phenotypes. Our goal was to assess the patterns of familial aggregation of three melanoma risk factors: great number of naevi (GNN), light phototype (LP) and high degree of sun exposure (HDSE).Familial aggregation of GNN, LP and HDSE was investigated in 66 French families with at least two CMM cases and was measured by the asssociation of the relatives' traits with the probands' traits, using the generalized estimating equations approach. The probands were the melanoma cases leading to ascertainment of the families, subdivided into cases (with the trait studied) and controls (without the trait).We found significant evidence for familial aggregation of GNN only among sibs (OR = 3.7, 95% CI : 1.4-10.5, P = 0.01), of LP among blood relatives (OR = 3.8, 95% CI : 1.8-8.0, P = 0.004) and of HDSE among blood relatives (OR = 4.5, 95% CI : 2.1-9.9, P < 0.001) and spouses (OR = 44.3, 95% CI : 5.1-382.2, P < 10(-3)). These results suggest that genetic factors might account for the clustering of GNN and LP and shared environment for the aggregation of HDSE. The GNN clustering was lower in families with increasing numbers of CMM (>/=3 cases) or presence of p16 mutations, the opposite being observed for LP and HDSE. Moreover, the familial aggregation of LP was significantly lower in families with highly sun-exposed members.Melanoma might not only result from specific genetic and environmental factors but also from those underlying melanoma-associated traits involving complex gene-gene and gene-environment interactions." @default.
• W2120190485 created "2016-06-24" @default.
• W2120190485 creator A5008535874 @default.
• W2120190485 creator A5036790641 @default.
• W2120190485 creator A5056723192 @default.
• W2120190485 creator A5057231943 @default.
• W2120190485 creator A5057596428 @default.
• W2120190485 creator A5074877417 @default.
• W2120190485 date "2000-06-01" @default.
• W2120190485 modified "2023-10-17" @default.
• W2120190485 title "Patterns of familial aggregation of three melanoma risk factors: great number of naevi, light phototype and high degree of sun exposure" @default.
• W2120190485 cites W135677969 @default.
• W2120190485 cites W1486632619 @default.
• W2120190485 cites W1492157159 @default.
• W2120190485 cites W1513181079 @default.
• W2120190485 cites W1916201704 @default.
• W2120190485 cites W1946633045 @default.
• W2120190485 cites W1971512164 @default.
• W2120190485 cites W1981605211 @default.
• W2120190485 cites W1983034555 @default.
• W2120190485 cites W1984573276 @default.
• W2120190485 cites W1984925885 @default.
• W2120190485 cites W1985779824 @default.
• W2120190485 cites W1992216855 @default.
• W2120190485 cites W2003659253 @default.
• W2120190485 cites W2008377798 @default.
• W2120190485 cites W2017365751 @default.
• W2120190485 cites W2034470478 @default.
• W2120190485 cites W2037459514 @default.
• W2120190485 cites W204080847 @default.
• W2120190485 cites W2045011028 @default.
• W2120190485 cites W2051506850 @default.
• W2120190485 cites W2068952252 @default.
• W2120190485 cites W2079482660 @default.
• W2120190485 cites W2086773265 @default.
• W2120190485 cites W2104204917 @default.
• W2120190485 cites W2106570276 @default.
• W2120190485 cites W2123444949 @default.
• W2120190485 cites W212866534 @default.
• W2120190485 cites W2137370771 @default.
• W2120190485 cites W2143258564 @default.
• W2120190485 cites W2148780072 @default.
• W2120190485 cites W2149860264 @default.
• W2120190485 cites W2160584494 @default.
• W2120190485 cites W2280565777 @default.
• W2120190485 cites W2281966796 @default.
• W2120190485 doi "https://doi.org/10.1093/ije/29.3.408" @default.
• W2120190485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10869311" @default.
• W2120190485 hasPublicationYear "2000" @default.
• W2120190485 type Work @default.
• W2120190485 sameAs 2120190485 @default.
• W2120190485 citedByCount "21" @default.
• W2120190485 countsByYear W21201904852013 @default.
• W2120190485 countsByYear W21201904852016 @default.
• W2120190485 crossrefType "journal-article" @default.
• W2120190485 hasAuthorship W2120190485A5008535874 @default.
• W2120190485 hasAuthorship W2120190485A5036790641 @default.
• W2120190485 hasAuthorship W2120190485A5056723192 @default.
• W2120190485 hasAuthorship W2120190485A5057231943 @default.
• W2120190485 hasAuthorship W2120190485A5057596428 @default.
• W2120190485 hasAuthorship W2120190485A5074877417 @default.
• W2120190485 hasBestOaLocation W21201904851 @default.
• W2120190485 hasConcept C104317684 @default.
• W2120190485 hasConcept C106934330 @default.
• W2120190485 hasConcept C126322002 @default.
• W2120190485 hasConcept C144024400 @default.
• W2120190485 hasConcept C149923435 @default.
• W2120190485 hasConcept C16005928 @default.
• W2120190485 hasConcept C188997412 @default.
• W2120190485 hasConcept C199360897 @default.
• W2120190485 hasConcept C203083617 @default.
• W2120190485 hasConcept C2777658100 @default.
• W2120190485 hasConcept C2779134260 @default.
• W2120190485 hasConcept C2779862289 @default.
• W2120190485 hasConcept C2780846639 @default.
• W2120190485 hasConcept C2781179581 @default.
• W2120190485 hasConcept C41008148 @default.
• W2120190485 hasConcept C501734568 @default.
• W2120190485 hasConcept C502942594 @default.
• W2120190485 hasConcept C54355233 @default.
• W2120190485 hasConcept C71924100 @default.
• W2120190485 hasConcept C86803240 @default.
• W2120190485 hasConceptScore W2120190485C104317684 @default.
• W2120190485 hasConceptScore W2120190485C106934330 @default.
• W2120190485 hasConceptScore W2120190485C126322002 @default.
• W2120190485 hasConceptScore W2120190485C144024400 @default.
• W2120190485 hasConceptScore W2120190485C149923435 @default.
• W2120190485 hasConceptScore W2120190485C16005928 @default.
• W2120190485 hasConceptScore W2120190485C188997412 @default.
• W2120190485 hasConceptScore W2120190485C199360897 @default.
• W2120190485 hasConceptScore W2120190485C203083617 @default.
• W2120190485 hasConceptScore W2120190485C2777658100 @default.
• W2120190485 hasConceptScore W2120190485C2779134260 @default.
• W2120190485 hasConceptScore W2120190485C2779862289 @default.
• W2120190485 hasConceptScore W2120190485C2780846639 @default.
• W2120190485 hasConceptScore W2120190485C2781179581 @default.
• W2120190485 hasConceptScore W2120190485C41008148 @default.
• W2120190485 hasConceptScore W2120190485C501734568 @default.

• next