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- W2120252008 abstract "Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5- dione) is a natural biological active substance with an antioxidant activity. The ability of curcumin to inhibit the free radical mechanisms can be used in a prevention of diseases such as cancer and coronary heart disease. The UV-VIS spectrophotometric and chemiluminescent dynamic methods for determination of antioxidant activity of curcumin were developed. The spectrophotometric method includes investigation of the interaction between DNA, isolated from HL-60 cells, and curcumin. The decreasing of the absorption of curcumin in the presence of HL-60 DNA against the blank sample can be a measurement for some complex formation between curcumin and DNA. The chemiluminescent method involves three tests for detection of luminol - depending chemiluminescence on the base of model systems which generate superoxide, hydroxide and hypochlorite radicals. The strongest decay of chemilunimescence was registered at the highest concentration of curcumin (100 ?mol/L)." @default.
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- W2120252008 date "2012-01-01" @default.
- W2120252008 modified "2023-10-16" @default.
- W2120252008 title "Application of UV-Vis spectrophotometric and chemiluminescent methods for evaluation of the antioxidant action of curcumin" @default.
- W2120252008 doi "https://doi.org/10.2298/jsc110621032s" @default.
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