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• W2120307471 abstract "Abstract The relationship of fatty acids to the metabolism of the human heart has been investigated in 41 healthy fasting men. In some subjects low plasma free fatty acid (FFA) concentrations were produced by infusing nicotinic acid. There existed negative correlations between myocardial extraction of glucose, lactate and pyruvate and that of FFA. Furthermore significant negative linear relationships between myocardial extraction of glucose and lactate and that of FFA were also present on partial correlation analysis eliminating the influence of other carbohydrate substrates. Possible explanations for these findings were discussed. Myocardial extraction of oxygen was positively related to that of FFA at rest unrelated to heart rate. The possibility, and its clinical implications, that FFA may increase myocardial oxygen requirements was discussed." @default.
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• W2120307471 date "1973-01-12" @default.
• W2120307471 modified "2023-10-16" @default.
• W2120307471 title "FATTY ACID AS A DETERMINANT OF MYOCARDIAL SUBSTRATE AND OXYGEN METABOLISM IN MAN AT REST AND DURING PROLONGED EXERCISE" @default.
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• W2120307471 doi "https://doi.org/10.1111/j.0954-6820.1973.tb10543.x" @default.
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