FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120317335> ?p ?o ?g. }

• W2120317335 endingPage "2268" @default.
• W2120317335 startingPage "2259" @default.
• W2120317335 abstract "In the assessment of immunity to the encapsulated virulent strain of Klebsiella pneumoniae and as avirulent mutant defective for capsular polysaccharide (CPS), killed bacterial vaccine of both strains could protect mice equally against challenge with 100 × LD50 of encapsulated wild strain. Antisera to each strain conferred the same level of protection on naive mice upon transfer; the protective anti-mutant serum was highly capable of opsonizing the encapsulated bacteria. In addition to the common antigenic components shared by both strains, the wild strain had antigen(s) unrelated to the mutant since the protective capacity of the anti-wild serum was not affected by preabsorption with the mutant strain; the protection conferred by the anti-mutant serum was mediated by antibodies against non-capsular antigens since the antiserum did not contain antibodies against purified CPS detectable by ELISA. As possible candidates among the non-capsular antigens, outer-membrane proteins (OMPs) extracted from the mutant strain were examined for their immunogenicity. Immunoblotting of the protein-containing fraction and ELISA using LPS-free OMP suggested that a number of proteins were involved in the immune response evoked by K. pneumoniae. Furthermore, mice immunized with OMP or anti-OMP serum could overcome a lethal challenge with the wild strain. These results indicated that OMPs of K. pneumoniae are implicated as the protective antigens and may pave the way for the development of non-capsular, proteinaceous vaccines." @default.
• W2120317335 created "2016-06-24" @default.
• W2120317335 creator A5002165563 @default.
• W2120317335 creator A5010807637 @default.
• W2120317335 creator A5014270152 @default.
• W2120317335 creator A5020284953 @default.
• W2120317335 creator A5022125728 @default.
• W2120317335 date "1989-08-01" @default.
• W2120317335 modified "2023-10-15" @default.
• W2120317335 title "Role of Antibodies against Outer-membrane Proteins in Murine Resistance to Infection with Encapsulated Klebsiella pneumoniae" @default.
• W2120317335 cites W145226427 @default.
• W2120317335 cites W1565712096 @default.
• W2120317335 cites W1792036402 @default.
• W2120317335 cites W1849835585 @default.
• W2120317335 cites W1852058150 @default.
• W2120317335 cites W1925369132 @default.
• W2120317335 cites W1932547257 @default.
• W2120317335 cites W1952620523 @default.
• W2120317335 cites W1960170507 @default.
• W2120317335 cites W1968834637 @default.
• W2120317335 cites W1983885661 @default.
• W2120317335 cites W2019918449 @default.
• W2120317335 cites W2022431667 @default.
• W2120317335 cites W2041677729 @default.
• W2120317335 cites W2078127817 @default.
• W2120317335 cites W2089604087 @default.
• W2120317335 cites W2097586470 @default.
• W2120317335 cites W2100837269 @default.
• W2120317335 cites W2101108802 @default.
• W2120317335 cites W2114089140 @default.
• W2120317335 cites W2115177265 @default.
• W2120317335 cites W2120190285 @default.
• W2120317335 cites W2128750132 @default.
• W2120317335 cites W2157310075 @default.
• W2120317335 cites W2237631740 @default.
• W2120317335 cites W2256756668 @default.
• W2120317335 cites W2297540397 @default.
• W2120317335 cites W2321064560 @default.
• W2120317335 doi "https://doi.org/10.1099/00221287-135-8-2259" @default.
• W2120317335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2699330" @default.
• W2120317335 hasPublicationYear "1989" @default.
• W2120317335 type Work @default.
• W2120317335 sameAs 2120317335 @default.
• W2120317335 citedByCount "10" @default.
• W2120317335 countsByYear W21203173352012 @default.
• W2120317335 countsByYear W21203173352019 @default.
• W2120317335 countsByYear W21203173352020 @default.
• W2120317335 countsByYear W21203173352022 @default.
• W2120317335 countsByYear W21203173352023 @default.
• W2120317335 crossrefType "journal-article" @default.
• W2120317335 hasAuthorship W2120317335A5002165563 @default.
• W2120317335 hasAuthorship W2120317335A5010807637 @default.
• W2120317335 hasAuthorship W2120317335A5014270152 @default.
• W2120317335 hasAuthorship W2120317335A5020284953 @default.
• W2120317335 hasAuthorship W2120317335A5022125728 @default.
• W2120317335 hasBestOaLocation W21203173351 @default.
• W2120317335 hasConcept C104317684 @default.
• W2120317335 hasConcept C105702510 @default.
• W2120317335 hasConcept C143065580 @default.
• W2120317335 hasConcept C146587185 @default.
• W2120317335 hasConcept C147483822 @default.
• W2120317335 hasConcept C159047783 @default.
• W2120317335 hasConcept C159654299 @default.
• W2120317335 hasConcept C203014093 @default.
• W2120317335 hasConcept C2777058267 @default.
• W2120317335 hasConcept C2778022156 @default.
• W2120317335 hasConcept C2779341262 @default.
• W2120317335 hasConcept C2780868878 @default.
• W2120317335 hasConcept C523546767 @default.
• W2120317335 hasConcept C54355233 @default.
• W2120317335 hasConcept C547475151 @default.
• W2120317335 hasConcept C55493867 @default.
• W2120317335 hasConcept C60987743 @default.
• W2120317335 hasConcept C86803240 @default.
• W2120317335 hasConcept C8891405 @default.
• W2120317335 hasConcept C89423630 @default.
• W2120317335 hasConcept C91523082 @default.
• W2120317335 hasConceptScore W2120317335C104317684 @default.
• W2120317335 hasConceptScore W2120317335C105702510 @default.
• W2120317335 hasConceptScore W2120317335C143065580 @default.
• W2120317335 hasConceptScore W2120317335C146587185 @default.
• W2120317335 hasConceptScore W2120317335C147483822 @default.
• W2120317335 hasConceptScore W2120317335C159047783 @default.
• W2120317335 hasConceptScore W2120317335C159654299 @default.
• W2120317335 hasConceptScore W2120317335C203014093 @default.
• W2120317335 hasConceptScore W2120317335C2777058267 @default.
• W2120317335 hasConceptScore W2120317335C2778022156 @default.
• W2120317335 hasConceptScore W2120317335C2779341262 @default.
• W2120317335 hasConceptScore W2120317335C2780868878 @default.
• W2120317335 hasConceptScore W2120317335C523546767 @default.
• W2120317335 hasConceptScore W2120317335C54355233 @default.
• W2120317335 hasConceptScore W2120317335C547475151 @default.
• W2120317335 hasConceptScore W2120317335C55493867 @default.
• W2120317335 hasConceptScore W2120317335C60987743 @default.
• W2120317335 hasConceptScore W2120317335C86803240 @default.
• W2120317335 hasConceptScore W2120317335C8891405 @default.
• W2120317335 hasConceptScore W2120317335C89423630 @default.
• W2120317335 hasConceptScore W2120317335C91523082 @default.

• next