Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120364024> ?p ?o ?g. }
- W2120364024 endingPage "189" @default.
- W2120364024 startingPage "189" @default.
- W2120364024 abstract "Considerations in selecting rapid-onset opioids for the management of breakthrough pain Howard S SmithDepartments of Anesthesiology, Medicine, and Physical Medicine and Rehabilitation Albany Medical College, Albany, NY, USAAbstract: Breakthrough pain (BTP) is a transitory pain that occurs despite the use of long-term, around-the-clock analgesia. It is highly prevalent in certain populations and places a significant burden on patients, their families, caregivers, and health-care systems. Despite its prevalence and impact, BTP is sometimes unrecognized and often undertreated. Various formulations of fentanyl – a rapid-onset opioid with short duration of action – are available for the management of BTP. The efficacy of formulations using transmucosal, transbuccal, sublingual, and intranasal administration routes has been demonstrated for BTP treatment in clinical trials. However, a lack of head-to-head trials evaluating their relative efficacy makes it challenging for physicians to reach informed decisions on the most efficacious intervention for individual patients. In the absence of clear data on the relative efficacy of fentanyl formulations, prescribing decisions need to be based on physician understanding and experience and product cost and availability, taking into account the individual patient's needs, the ability of the patient or caregivers to administer medication, and the patient's wishes. This review evaluates current pharmacologic methods of alleviating BTP and discusses factors that should be considered when selecting the most appropriate formulation for individual patients. With the range of fentanyl formulations available, it is now possible to successfully address BTP in the majority of patients.Keywords: rapid-onset opioid, breakthrough pain, pain, fentanyl" @default.
- W2120364024 created "2016-06-24" @default.
- W2120364024 creator A5058649092 @default.
- W2120364024 date "2013-03-01" @default.
- W2120364024 modified "2023-09-29" @default.
- W2120364024 title "Considerations in selecting rapid-onset opioids for the management of breakthrough pain" @default.
- W2120364024 cites W1491929107 @default.
- W2120364024 cites W1506722149 @default.
- W2120364024 cites W1573834610 @default.
- W2120364024 cites W1581014376 @default.
- W2120364024 cites W1602531667 @default.
- W2120364024 cites W162216843 @default.
- W2120364024 cites W1670029314 @default.
- W2120364024 cites W1854233685 @default.
- W2120364024 cites W1963668674 @default.
- W2120364024 cites W1965442837 @default.
- W2120364024 cites W1965473919 @default.
- W2120364024 cites W1972367702 @default.
- W2120364024 cites W1975976481 @default.
- W2120364024 cites W1976427793 @default.
- W2120364024 cites W1979205093 @default.
- W2120364024 cites W1983215991 @default.
- W2120364024 cites W1990596188 @default.
- W2120364024 cites W1991129784 @default.
- W2120364024 cites W1999275813 @default.
- W2120364024 cites W2001086017 @default.
- W2120364024 cites W2006980284 @default.
- W2120364024 cites W2011613279 @default.
- W2120364024 cites W2023088935 @default.
- W2120364024 cites W2023671892 @default.
- W2120364024 cites W2028501562 @default.
- W2120364024 cites W2029493179 @default.
- W2120364024 cites W2032538158 @default.
- W2120364024 cites W2035102825 @default.
- W2120364024 cites W2037560904 @default.
- W2120364024 cites W2038971432 @default.
- W2120364024 cites W2039691198 @default.
- W2120364024 cites W2041840116 @default.
- W2120364024 cites W2045560091 @default.
- W2120364024 cites W2051739365 @default.
- W2120364024 cites W2053951172 @default.
- W2120364024 cites W2054082316 @default.
- W2120364024 cites W2055639620 @default.
- W2120364024 cites W2057628301 @default.
- W2120364024 cites W2058784072 @default.
- W2120364024 cites W2060222819 @default.
- W2120364024 cites W2060710959 @default.
- W2120364024 cites W2061776351 @default.
- W2120364024 cites W2064720340 @default.
- W2120364024 cites W206566180 @default.
- W2120364024 cites W2070414986 @default.
- W2120364024 cites W2075716831 @default.
- W2120364024 cites W2082949601 @default.
- W2120364024 cites W2082996698 @default.
- W2120364024 cites W2083010739 @default.
- W2120364024 cites W2085338031 @default.
- W2120364024 cites W2085556814 @default.
- W2120364024 cites W2090317969 @default.
- W2120364024 cites W2090900919 @default.
- W2120364024 cites W2110502963 @default.
- W2120364024 cites W2120849181 @default.
- W2120364024 cites W2123280399 @default.
- W2120364024 cites W2127078023 @default.
- W2120364024 cites W2132742763 @default.
- W2120364024 cites W2135516229 @default.
- W2120364024 cites W2137999087 @default.
- W2120364024 cites W2147182623 @default.
- W2120364024 cites W2148323998 @default.
- W2120364024 cites W2148409500 @default.
- W2120364024 cites W2154719748 @default.
- W2120364024 cites W2161528864 @default.
- W2120364024 cites W2164109641 @default.
- W2120364024 cites W2313717767 @default.
- W2120364024 cites W2331127269 @default.
- W2120364024 cites W2332698029 @default.
- W2120364024 cites W290308871 @default.
- W2120364024 doi "https://doi.org/10.2147/jpr.s40745" @default.
- W2120364024 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3594916" @default.
- W2120364024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23503653" @default.
- W2120364024 hasPublicationYear "2013" @default.
- W2120364024 type Work @default.
- W2120364024 sameAs 2120364024 @default.
- W2120364024 citedByCount "32" @default.
- W2120364024 countsByYear W21203640242013 @default.
- W2120364024 countsByYear W21203640242014 @default.
- W2120364024 countsByYear W21203640242015 @default.
- W2120364024 countsByYear W21203640242016 @default.
- W2120364024 countsByYear W21203640242017 @default.
- W2120364024 countsByYear W21203640242018 @default.
- W2120364024 countsByYear W21203640242021 @default.
- W2120364024 countsByYear W21203640242022 @default.
- W2120364024 crossrefType "journal-article" @default.
- W2120364024 hasAuthorship W2120364024A5058649092 @default.
- W2120364024 hasBestOaLocation W21203640241 @default.
- W2120364024 hasConcept C118552586 @default.
- W2120364024 hasConcept C126322002 @default.
- W2120364024 hasConcept C142724271 @default.
- W2120364024 hasConcept C160735492 @default.