FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120364592> ?p ?o ?g. }

• W2120364592 endingPage "238" @default.
• W2120364592 startingPage "231" @default.
• W2120364592 abstract "Functional neuroimaging studies have implicated the insular cortex in emotional processing, including the evaluation of one's own emotion, as well as in the neurobiology of major depressive disorder (MDD). Nevertheless, it remains largely unknown whether MDD patients exhibit morphologic changes of the insular cortex, and whether such changes reflect state or trait markers of the disorder. We delineated the anterior and posterior insular cortices using magnetic resonance imaging in 29 currently depressed patients (mean age = 32.5 years, 7 males), 27 remitted depressed patients (mean age = 35.1 years, 9 males), and 33 age- and gender-matched healthy control subjects (mean age = 34.0 years, 12 males). Both current and remitted MDD patients showed significant volume reduction of the left anterior insular cortex as compared with healthy controls, but there was no group difference in the posterior insular cortex volume. Insular volumes did not correlate with the severity of depressive symptoms. Furthermore, the presence of melancholia and co-morbidity with anxiety disorders did not affect insular cortex volumes. Although there was no difference in the insular cortex volume between medicated and unmedicated patients, a comprehensive investigation of medication effects was not possible, as complete data (e.g., dose, duration) were not available. These findings suggest that the morphologic abnormality of the anterior insular cortex, which plays a major role in introspection and emotional control, may be a trait-related marker of vulnerability to major depression, supporting the notion that MDD involves pathological alterations of limbic and related cortical structures." @default.
• W2120364592 created "2016-06-24" @default.
• W2120364592 creator A5011264157 @default.
• W2120364592 creator A5030179420 @default.
• W2120364592 creator A5055959065 @default.
• W2120364592 creator A5068573034 @default.
• W2120364592 creator A5073150594 @default.
• W2120364592 creator A5075071337 @default.
• W2120364592 creator A5075623618 @default.
• W2120364592 creator A5077268112 @default.
• W2120364592 creator A5087010551 @default.
• W2120364592 date "2010-03-01" @default.
• W2120364592 modified "2023-10-07" @default.
• W2120364592 title "Volumetric MRI study of the insular cortex in individuals with current and past major depression" @default.
• W2120364592 cites W1517011095 @default.
• W2120364592 cites W1525298240 @default.
• W2120364592 cites W1892060126 @default.
• W2120364592 cites W1945514973 @default.
• W2120364592 cites W1973587070 @default.
• W2120364592 cites W1974235453 @default.
• W2120364592 cites W1980508260 @default.
• W2120364592 cites W1984907857 @default.
• W2120364592 cites W1990288178 @default.
• W2120364592 cites W1997245512 @default.
• W2120364592 cites W2000758625 @default.
• W2120364592 cites W2000871300 @default.
• W2120364592 cites W2002611894 @default.
• W2120364592 cites W2004785543 @default.
• W2120364592 cites W2014518515 @default.
• W2120364592 cites W2016793719 @default.
• W2120364592 cites W2022141086 @default.
• W2120364592 cites W2037327301 @default.
• W2120364592 cites W2039439336 @default.
• W2120364592 cites W2041435129 @default.
• W2120364592 cites W2043189909 @default.
• W2120364592 cites W2043277071 @default.
• W2120364592 cites W2050506045 @default.
• W2120364592 cites W2051309244 @default.
• W2120364592 cites W2059602652 @default.
• W2120364592 cites W2065267118 @default.
• W2120364592 cites W2067244840 @default.
• W2120364592 cites W2069247119 @default.
• W2120364592 cites W2090690633 @default.
• W2120364592 cites W2103991542 @default.
• W2120364592 cites W2105491962 @default.
• W2120364592 cites W2110402512 @default.
• W2120364592 cites W2117303562 @default.
• W2120364592 cites W2118248825 @default.
• W2120364592 cites W2121520936 @default.
• W2120364592 cites W2132156834 @default.
• W2120364592 cites W2137830721 @default.
• W2120364592 cites W2143977263 @default.
• W2120364592 cites W2144538553 @default.
• W2120364592 cites W2147711803 @default.
• W2120364592 cites W2147969224 @default.
• W2120364592 cites W2148639290 @default.
• W2120364592 cites W2164491634 @default.
• W2120364592 cites W2167633367 @default.
• W2120364592 cites W2168221314 @default.
• W2120364592 cites W2168309258 @default.
• W2120364592 cites W4229967315 @default.
• W2120364592 cites W4243565408 @default.
• W2120364592 cites W4292994367 @default.
• W2120364592 doi "https://doi.org/10.1016/j.jad.2009.06.003" @default.
• W2120364592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19540599" @default.
• W2120364592 hasPublicationYear "2010" @default.
• W2120364592 type Work @default.
• W2120364592 sameAs 2120364592 @default.
• W2120364592 citedByCount "92" @default.
• W2120364592 countsByYear W21203645922012 @default.
• W2120364592 countsByYear W21203645922013 @default.
• W2120364592 countsByYear W21203645922014 @default.
• W2120364592 countsByYear W21203645922015 @default.
• W2120364592 countsByYear W21203645922016 @default.
• W2120364592 countsByYear W21203645922017 @default.
• W2120364592 countsByYear W21203645922018 @default.
• W2120364592 countsByYear W21203645922019 @default.
• W2120364592 countsByYear W21203645922020 @default.
• W2120364592 countsByYear W21203645922021 @default.
• W2120364592 countsByYear W21203645922022 @default.
• W2120364592 countsByYear W21203645922023 @default.
• W2120364592 crossrefType "journal-article" @default.
• W2120364592 hasAuthorship W2120364592A5011264157 @default.
• W2120364592 hasAuthorship W2120364592A5030179420 @default.
• W2120364592 hasAuthorship W2120364592A5055959065 @default.
• W2120364592 hasAuthorship W2120364592A5068573034 @default.
• W2120364592 hasAuthorship W2120364592A5073150594 @default.
• W2120364592 hasAuthorship W2120364592A5075071337 @default.
• W2120364592 hasAuthorship W2120364592A5075623618 @default.
• W2120364592 hasAuthorship W2120364592A5077268112 @default.
• W2120364592 hasAuthorship W2120364592A5087010551 @default.
• W2120364592 hasConcept C118552586 @default.
• W2120364592 hasConcept C126322002 @default.
• W2120364592 hasConcept C139719470 @default.
• W2120364592 hasConcept C15744967 @default.
• W2120364592 hasConcept C162324750 @default.
• W2120364592 hasConcept C169760540 @default.
• W2120364592 hasConcept C207886595 @default.

• next