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• W2120573048 abstract "Dysgerminoma is the most common malignant germ cell tumor of the ovary. This malignancy can be associated with pure gonadal dysgenesis or Swyer syndrome, mixed gonadal dysgenesis and partial gonadal dysgenesis. Dysgerminoma developed in 3 phenotypic female patients with 46 XY pure gonadal dysgenesis. All patients presented first with abdominopelvic mass. Laparatomy was done. 46 XY karyotype was made by lymphocyte culture. Then these patients underwent gonadectomy that histopathology results were streak ovaries without evidence for malignancy. Two patients received postoperative adjuvant therapy. In Patients with Swyer syndrome the risk of dysgerminoma is high and gonadectomy is recommended. Also 5% of dysgerminomas are discovered in phenotypic female and 46 XY karyotype, thus in adolescent with dysgerminoimas and amenorrhea, karyotype should be done." @default.
• W2120573048 created "2016-06-24" @default.
• W2120573048 creator A5031957922 @default.
• W2120573048 creator A5090555015 @default.
• W2120573048 date "2007-06-23" @default.
• W2120573048 modified "2023-09-25" @default.
• W2120573048 title "Dysgerminoma in three patients with Swyer syndrome" @default.
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• W2120573048 doi "https://doi.org/10.1186/1477-7819-5-71" @default.
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