FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120718097> ?p ?o ?g. }

• W2120718097 endingPage "2262" @default.
• W2120718097 startingPage "2256" @default.
• W2120718097 abstract "Background Prolongation of the baseline ECG PR interval is frequently encountered among cardiac resynchronization therapy (CRT) recipients. There are conflicting data regarding the association of a prolonged PR interval with long-term clinical outcome in this patient group. Objective The purpose of this study was to compare clinical outcomes and response to CRT in patients with normal (<200 ms) vs prolonged (≥200 ms) baseline PR interval. Methods In this study, 283 patients (normal PR interval: n = 158; prolonged PR interval: n = 125) with documented baseline intrinsic PR interval were followed for 3 years after CRT implantation. The study population consisted of 24.7% women (mean age 66 ± 13 years, left ventricular ejection fraction 24% ± 7%). Results A Cox proportional hazard model identified baseline PR interval as a predictor of the composite end-point (all-cause mortality, heart failure hospitalization, left ventricular assist device implantation, and heart transplantation) in univariate analysis (hazard ratio [HR] 1.49, 95% confidence interval [CI] 1.02–2.17, P = .04) but not in multivariate analysis. It also predicted heart failure hospitalization in univariate (HR 1.6, 95% CI 1.1–2.4, P = .02) and multivariate analysis (HR 1.6, 95% CI 1.0–2.3, P = .03). A prolonged PR interval was associated with lower probability of reverse remodeling defined as ≥10% improvement in ejection fraction (64% vs 77%, P = .057), especially in patients with non–left bundle branch block ECG morphology (41% vs 68%, P = .03). Conclusion Among patients with CRT, a prolonged baseline PR interval is an independent predictor of worse prognosis and lower probability of reverse remodeling, especially for patients with non–left bundle branch block morphology on ECG. Prolongation of the baseline ECG PR interval is frequently encountered among cardiac resynchronization therapy (CRT) recipients. There are conflicting data regarding the association of a prolonged PR interval with long-term clinical outcome in this patient group. The purpose of this study was to compare clinical outcomes and response to CRT in patients with normal (<200 ms) vs prolonged (≥200 ms) baseline PR interval. In this study, 283 patients (normal PR interval: n = 158; prolonged PR interval: n = 125) with documented baseline intrinsic PR interval were followed for 3 years after CRT implantation. The study population consisted of 24.7% women (mean age 66 ± 13 years, left ventricular ejection fraction 24% ± 7%). A Cox proportional hazard model identified baseline PR interval as a predictor of the composite end-point (all-cause mortality, heart failure hospitalization, left ventricular assist device implantation, and heart transplantation) in univariate analysis (hazard ratio [HR] 1.49, 95% confidence interval [CI] 1.02–2.17, P = .04) but not in multivariate analysis. It also predicted heart failure hospitalization in univariate (HR 1.6, 95% CI 1.1–2.4, P = .02) and multivariate analysis (HR 1.6, 95% CI 1.0–2.3, P = .03). A prolonged PR interval was associated with lower probability of reverse remodeling defined as ≥10% improvement in ejection fraction (64% vs 77%, P = .057), especially in patients with non–left bundle branch block ECG morphology (41% vs 68%, P = .03). Among patients with CRT, a prolonged baseline PR interval is an independent predictor of worse prognosis and lower probability of reverse remodeling, especially for patients with non–left bundle branch block morphology on ECG." @default.
• W2120718097 created "2016-06-24" @default.
• W2120718097 creator A5001673231 @default.
• W2120718097 creator A5022138867 @default.
• W2120718097 creator A5022861745 @default.
• W2120718097 creator A5028052943 @default.
• W2120718097 creator A5036291074 @default.
• W2120718097 creator A5066983511 @default.
• W2120718097 creator A5067468230 @default.
• W2120718097 creator A5074094902 @default.
• W2120718097 creator A5090601076 @default.
• W2120718097 date "2015-11-01" @default.
• W2120718097 modified "2023-10-12" @default.
• W2120718097 title "Prognostic implication of baseline PR interval in cardiac resynchronization therapy recipients" @default.
• W2120718097 cites W1966023162 @default.
• W2120718097 cites W1966470544 @default.
• W2120718097 cites W1989034643 @default.
• W2120718097 cites W1995419596 @default.
• W2120718097 cites W1997875621 @default.
• W2120718097 cites W1998999499 @default.
• W2120718097 cites W2000390606 @default.
• W2120718097 cites W2005053320 @default.
• W2120718097 cites W2008965471 @default.
• W2120718097 cites W2026806373 @default.
• W2120718097 cites W2028327240 @default.
• W2120718097 cites W2032717020 @default.
• W2120718097 cites W2035667813 @default.
• W2120718097 cites W2047422067 @default.
• W2120718097 cites W2068989566 @default.
• W2120718097 cites W2074760813 @default.
• W2120718097 cites W2083424784 @default.
• W2120718097 cites W2100056258 @default.
• W2120718097 cites W2104300278 @default.
• W2120718097 cites W2128104918 @default.
• W2120718097 cites W2130840464 @default.
• W2120718097 cites W2130907431 @default.
• W2120718097 cites W2141895646 @default.
• W2120718097 cites W2146521529 @default.
• W2120718097 cites W2151056321 @default.
• W2120718097 cites W2162741079 @default.
• W2120718097 cites W2170757224 @default.
• W2120718097 cites W2548693925 @default.
• W2120718097 cites W36984294 @default.
• W2120718097 cites W2185646482 @default.
• W2120718097 doi "https://doi.org/10.1016/j.hrthm.2015.06.016" @default.
• W2120718097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26066291" @default.
• W2120718097 hasPublicationYear "2015" @default.
• W2120718097 type Work @default.
• W2120718097 sameAs 2120718097 @default.
• W2120718097 citedByCount "28" @default.
• W2120718097 countsByYear W21207180972015 @default.
• W2120718097 countsByYear W21207180972016 @default.
• W2120718097 countsByYear W21207180972017 @default.
• W2120718097 countsByYear W21207180972018 @default.
• W2120718097 countsByYear W21207180972019 @default.
• W2120718097 countsByYear W21207180972020 @default.
• W2120718097 countsByYear W21207180972021 @default.
• W2120718097 countsByYear W21207180972022 @default.
• W2120718097 countsByYear W21207180972023 @default.
• W2120718097 crossrefType "journal-article" @default.
• W2120718097 hasAuthorship W2120718097A5001673231 @default.
• W2120718097 hasAuthorship W2120718097A5022138867 @default.
• W2120718097 hasAuthorship W2120718097A5022861745 @default.
• W2120718097 hasAuthorship W2120718097A5028052943 @default.
• W2120718097 hasAuthorship W2120718097A5036291074 @default.
• W2120718097 hasAuthorship W2120718097A5066983511 @default.
• W2120718097 hasAuthorship W2120718097A5067468230 @default.
• W2120718097 hasAuthorship W2120718097A5074094902 @default.
• W2120718097 hasAuthorship W2120718097A5090601076 @default.
• W2120718097 hasConcept C126322002 @default.
• W2120718097 hasConcept C144301174 @default.
• W2120718097 hasConcept C164705383 @default.
• W2120718097 hasConcept C178697064 @default.
• W2120718097 hasConcept C207103383 @default.
• W2120718097 hasConcept C2776034619 @default.
• W2120718097 hasConcept C2777473070 @default.
• W2120718097 hasConcept C2777953023 @default.
• W2120718097 hasConcept C2778198053 @default.
• W2120718097 hasConcept C2778849806 @default.
• W2120718097 hasConcept C2908647359 @default.
• W2120718097 hasConcept C38180746 @default.
• W2120718097 hasConcept C44249647 @default.
• W2120718097 hasConcept C50382708 @default.
• W2120718097 hasConcept C71924100 @default.
• W2120718097 hasConcept C78085059 @default.
• W2120718097 hasConcept C84393581 @default.
• W2120718097 hasConcept C99454951 @default.
• W2120718097 hasConceptScore W2120718097C126322002 @default.
• W2120718097 hasConceptScore W2120718097C144301174 @default.
• W2120718097 hasConceptScore W2120718097C164705383 @default.
• W2120718097 hasConceptScore W2120718097C178697064 @default.
• W2120718097 hasConceptScore W2120718097C207103383 @default.
• W2120718097 hasConceptScore W2120718097C2776034619 @default.
• W2120718097 hasConceptScore W2120718097C2777473070 @default.
• W2120718097 hasConceptScore W2120718097C2777953023 @default.
• W2120718097 hasConceptScore W2120718097C2778198053 @default.
• W2120718097 hasConceptScore W2120718097C2778849806 @default.
• W2120718097 hasConceptScore W2120718097C2908647359 @default.

• next