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- W2120722877 abstract "Sex determination is important in forensic cases of missing persons, rape or to establish the sexual identity. There are molecular tools to determine the sex such as the simultaneous quantification of autosomal DNA and Y chromosome and the typification of amelogenin and Y chromosome markers but do not always yield accurate data on the determination of whether the individual is male or female and this can be related to mutational effects or in the possible discrepancies between the biological gender and the legal gender. Also in mixtures profiles cases, where there is a female predominant profile, may have problems in identifying the male component in the amelogenin and not always is successful the amplification of Y chromosome specific markers whose outcome can confirm the presence of a male profile.In this research were proposed different cases related to sex determination associated with mutations in the amelogenin sex marker or in theirs primers annealing regions, hermaphroditism, aneuploidies and the potential results of the forensic genetic routine markers whose interpretation should be used carefully to avoid misunderstanding in our reports." @default.
- W2120722877 created "2016-06-24" @default.
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- W2120722877 date "2013-01-01" @default.
- W2120722877 modified "2023-09-25" @default.
- W2120722877 title "Sex determination problems in forensic genetic analysis" @default.
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- W2120722877 doi "https://doi.org/10.1016/j.fsigss.2013.10.178" @default.
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