FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2120825136> ?p ?o ?g. }

• W2120825136 endingPage "83" @default.
• W2120825136 startingPage "79" @default.
• W2120825136 abstract "In recent years, three national gastroenterology societies established guidelines for the diagnosis and therapy of pancreatic exocrine insufficiency (PEI). In addition, the Cochrane Collaboration issued a review.The purpose of this paper is to present an overview of the recommendations and concordance between the four recent published guidelines and stimulate further discussion.A review of the Australian, German and Italian guidelines and the Cochrane review was conducted, and a synthesis was made of common statements.There is a high degree of agreement on almost all items within these guidelines, both in the diagnosis of PEI and in terms of therapy and approach to management of PEI. In addition, novel emerging developments are highlighted, such as the fecal elastase-1 test, which is widely used but is not suitable for measuring mild-to-moderate PEI despite its ability to positively establish the diagnosis of severe PEI. One of the few novel tests proving to be useful is the (13)C mixed-chain triglycerides (MCT) breath test. This test, albeit an excellent quantitative test, is not widely used and is rarely available. The use of this test is making it apparent that there is a difference between treating the symptoms of PEI and treating malnutrition, the broader underlying defect. This may have direct consequences for the dosing of pancreatic enzymes (pancreatin), in that the consensus starting dose of all guidelines may be too low for some patients. Although chronic pancreatitis in adults and cystic fibrosis in children account for the main evidence base used for PEI, other indications are also discussed.There is good concordance between recommendations provided by international groups. More prospective studies are required in many areas, including the use of pancreatic enzymes in other gastrointestinal disorders, such as celiac disease and irritable bowel syndrome (IBS). We also need to assess the feasibility of the (13)C MCT breath test. At the same time, it needs to be confirmed that higher doses of pancreatic enzymes are really necessary to not only relieve the symptoms of PEI but also treat malnutrition appropriately." @default.
• W2120825136 created "2016-06-24" @default.
• W2120825136 creator A5028819527 @default.
• W2120825136 creator A5053561113 @default.
• W2120825136 creator A5067118869 @default.
• W2120825136 date "2013-04-01" @default.
• W2120825136 modified "2023-10-17" @default.
• W2120825136 title "Synopsis of recent guidelines on pancreatic exocrine insufficiency" @default.
• W2120825136 cites W1565636942 @default.
• W2120825136 cites W1861439258 @default.
• W2120825136 cites W1880459926 @default.
• W2120825136 cites W1967449094 @default.
• W2120825136 cites W1967628980 @default.
• W2120825136 cites W1993122603 @default.
• W2120825136 cites W1993414114 @default.
• W2120825136 cites W1993726826 @default.
• W2120825136 cites W2002500439 @default.
• W2120825136 cites W2005155537 @default.
• W2120825136 cites W2015544914 @default.
• W2120825136 cites W2036163888 @default.
• W2120825136 cites W2045572961 @default.
• W2120825136 cites W2046756574 @default.
• W2120825136 cites W2056571582 @default.
• W2120825136 cites W2061456247 @default.
• W2120825136 cites W2061795839 @default.
• W2120825136 cites W2075970069 @default.
• W2120825136 cites W2077083610 @default.
• W2120825136 cites W2092939817 @default.
• W2120825136 cites W2095730112 @default.
• W2120825136 cites W2117093474 @default.
• W2120825136 cites W2157194243 @default.
• W2120825136 cites W2159828651 @default.
• W2120825136 cites W2171023809 @default.
• W2120825136 cites W2322702493 @default.
• W2120825136 doi "https://doi.org/10.1177/2050640613476500" @default.
• W2120825136 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4040730" @default.
• W2120825136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24917944" @default.
• W2120825136 hasPublicationYear "2013" @default.
• W2120825136 type Work @default.
• W2120825136 sameAs 2120825136 @default.
• W2120825136 citedByCount "54" @default.
• W2120825136 countsByYear W21208251362013 @default.
• W2120825136 countsByYear W21208251362014 @default.
• W2120825136 countsByYear W21208251362015 @default.
• W2120825136 countsByYear W21208251362017 @default.
• W2120825136 countsByYear W21208251362018 @default.
• W2120825136 countsByYear W21208251362019 @default.
• W2120825136 countsByYear W21208251362020 @default.
• W2120825136 countsByYear W21208251362021 @default.
• W2120825136 countsByYear W21208251362022 @default.
• W2120825136 countsByYear W21208251362023 @default.
• W2120825136 crossrefType "journal-article" @default.
• W2120825136 hasAuthorship W2120825136A5028819527 @default.
• W2120825136 hasAuthorship W2120825136A5053561113 @default.
• W2120825136 hasAuthorship W2120825136A5067118869 @default.
• W2120825136 hasBestOaLocation W21208251361 @default.
• W2120825136 hasConcept C126322002 @default.
• W2120825136 hasConcept C160798450 @default.
• W2120825136 hasConcept C17744445 @default.
• W2120825136 hasConcept C177713679 @default.
• W2120825136 hasConcept C189708586 @default.
• W2120825136 hasConcept C199539241 @default.
• W2120825136 hasConcept C2775967933 @default.
• W2120825136 hasConcept C2776938444 @default.
• W2120825136 hasConcept C2777152358 @default.
• W2120825136 hasConcept C2777675875 @default.
• W2120825136 hasConcept C2779473830 @default.
• W2120825136 hasConcept C3019860435 @default.
• W2120825136 hasConcept C71924100 @default.
• W2120825136 hasConcept C90924648 @default.
• W2120825136 hasConceptScore W2120825136C126322002 @default.
• W2120825136 hasConceptScore W2120825136C160798450 @default.
• W2120825136 hasConceptScore W2120825136C17744445 @default.
• W2120825136 hasConceptScore W2120825136C177713679 @default.
• W2120825136 hasConceptScore W2120825136C189708586 @default.
• W2120825136 hasConceptScore W2120825136C199539241 @default.
• W2120825136 hasConceptScore W2120825136C2775967933 @default.
• W2120825136 hasConceptScore W2120825136C2776938444 @default.
• W2120825136 hasConceptScore W2120825136C2777152358 @default.
• W2120825136 hasConceptScore W2120825136C2777675875 @default.
• W2120825136 hasConceptScore W2120825136C2779473830 @default.
• W2120825136 hasConceptScore W2120825136C3019860435 @default.
• W2120825136 hasConceptScore W2120825136C71924100 @default.
• W2120825136 hasConceptScore W2120825136C90924648 @default.
• W2120825136 hasFunder F4320327571 @default.
• W2120825136 hasIssue "2" @default.
• W2120825136 hasLocation W21208251361 @default.
• W2120825136 hasLocation W21208251362 @default.
• W2120825136 hasLocation W21208251363 @default.
• W2120825136 hasLocation W21208251364 @default.
• W2120825136 hasOpenAccess W2120825136 @default.
• W2120825136 hasPrimaryLocation W21208251361 @default.
• W2120825136 hasRelatedWork W1588012644 @default.
• W2120825136 hasRelatedWork W2001960390 @default.
• W2120825136 hasRelatedWork W2058832876 @default.
• W2120825136 hasRelatedWork W2072037150 @default.
• W2120825136 hasRelatedWork W2075105997 @default.
• W2120825136 hasRelatedWork W2085642903 @default.

• next