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- W2120848404 abstract "A series of novel 6-[(1,3,4-thiadiazol-2-yl)sulfanyl]-7-phenylpyrazolo[1,5-a]pyrimidines, 5-phenyl-6-[(1,3,4-thiadiazol-2-yl)sulfanyl]imidazo[1,2-a]pyrimidines, and 2-phenyl-3-[(1,3,4-thiadiazol-2-yl)sulfanyl]pyrimido[1,2-a]benzimidazoles have been synthesized in four steps starting with 2-hydroxyacetophenone. The intermediate 3-[(1,3,4-thiadiazol-2-yl)sulfanyl]-4H-1-benzopyran-4-ones reacted with pyrazol-3-amines, 5-methylpyrazol-3-amine, and 1H-imidazol-2-amine, 1H-benzimidazol-2-amine via a cyclocondensation to give the title compounds in the presence of MeONa as base, respectively. The approach affords the target compounds in acceptable-to-good yields. The new compounds were characterized by their IR, NMR, and HR mass spectra." @default.
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- W2120848404 date "2012-06-01" @default.
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- W2120848404 title "Synthesis of Novel Disubstituted Pyrazolo[1,5-a]pyrimidines, Imidazo[1,2-a]pyrimidines, and Pyrimido[1,2-a]benzimidazoles Containing Thioether and Aryl Moieties" @default.
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- W2120848404 doi "https://doi.org/10.1002/hlca.201100495" @default.
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