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• W2120960501 endingPage "H1106" @default.
• W2120960501 startingPage "H1097" @default.
• W2120960501 abstract "A scanning phosphorescence quenching microscopy technique, designed to prevent accumulated O 2 consumption by the method, was applied to Po 2 measurements in mesenteric tissue. In an attempt to further increase the accuracy of the measurements, albumin-bound probe was topically applied to the tissue and an objective-mounted pressurized bag was used to reduce the oxygen transport bypass through the thin layer of fluid over the mesentery. Po 2 was measured at multiple sites perpendicular to the blood/wall interface in the vicinity of 84 mesenteric arterioles (7–39 μm in diameter) at distances of 5, 15, 30, 60, 120, and 180 μm in seven anesthetized Sprague-Dawley rats, thereby creating Po 2 profiles. Interstitial Po 2 above and immediately beside arterioles was found to agree with known intravascular values. No significant difference in Po 2 profiles was found between small and large arterioles, indicating a small longitudinal Po 2 gradient in the precapillary mesenteric microvasculature. In addition, the Po 2 profiles were used to calculate oxygen consumption in the mesenteric tissue (56–65 nl O 2 ·cm −3 ·s −1 ). Correction of these values for contamination with ambient oxygen yielded an oxygen consumption rate of 60–68 nl O 2 ·cm −3 ·s −1 , the maximal limit for consumption in the mesentery. The results were compared with measurements made by other workers in regard to the employed techniques." @default.
• W2120960501 created "2016-06-24" @default.
• W2120960501 creator A5069379736 @default.
• W2120960501 creator A5081531632 @default.
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• W2120960501 date "2007-08-01" @default.
• W2120960501 modified "2023-10-18" @default.
• W2120960501 title "P<scp>o</scp>₂profiles near arterioles and tissue oxygen consumption in rat mesentery" @default.
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• W2120960501 doi "https://doi.org/10.1152/ajpheart.00077.2007" @default.
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