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• W2121036626 abstract "The stratum corneum is a complex biological material characterized by very low permeability to water and most other molecules. This material may be thought of as a 'porous medium' composed of impermeable and permeable regions. Intercellular lipid membranes in the stratum corneum are postulated to exist in a mixture of two phases: solid (i.e. impermeable) and liquid crystalline (permeable). The corneocyte envelope is classified as impermeable. Diffusion mechanisms of solutes within, across and between the intercellular lamellae are discussed. This model represents a refinement of previous theories about the physical structures responsible for the low observed permeability of the stratum corneum." @default.
• W2121036626 created "2016-06-24" @default.
• W2121036626 creator A5040017067 @default.
• W2121036626 creator A5044994470 @default.
• W2121036626 date "2000-05-10" @default.
• W2121036626 modified "2023-09-25" @default.
• W2121036626 title "Hypothesis: The epidermal permeability barrier is a porous medium" @default.
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• W2121036626 doi "https://doi.org/10.1080/000155500750042808" @default.
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