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- W2121036679 abstract "Interaction between the flavones casticin and artemetin and the antimalarial activity of chloroquine and qinghaosu (QHS) was examined using an in vitro growth assay based on [3H]hypoxanthine incorporation in synchronized cultures of a cloned line of Plasmodium falciparum. Casticin, and to a lesser extent artemetin, selectively enhanced the inhibition of growth by QHS, but had little effect on the activity of chloroquine. The findings suggest that flavones indigenous to Artemisia annua, from which QHS is isolated, might significantly alter the clinical potential of this novel antimalarial drug in the treatment of chloroquine-resistant malaria." @default.
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- W2121036679 date "1987-01-01" @default.
- W2121036679 modified "2023-10-07" @default.
- W2121036679 title "Potentiation of the antimalarial activity of qinghaosu by methoxylated flavones" @default.
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- W2121036679 doi "https://doi.org/10.1016/0035-9203(87)90161-1" @default.
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