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• W2121051882 endingPage "1395" @default.
• W2121051882 startingPage "1383" @default.
• W2121051882 abstract "For human embryonic stem cells (hESCs) to be used clinically, it is imperative that immune responses evoked by hESCs and their derivates after transplantation should be prevented. Human leukocyte antigens (HLA) and ABO blood group antigens are important histocompatibility factors in graft rejection. HLA matching between recipient and unrelated donors, in particular, is important in improving outcomes in hematopoietic cell transplantation (HCT). We have established and successfully maintained 29 hESC lines and analyzed the HLA and ABO genotypes of these lines. HLA-A, -B, -C and -DR (DRB1) genotyping was performed by polymerase chain reaction (PCR) sequence-based typing and ABO genotyping was carried out by PCR restriction fragment length polymorphism methods. To determine what proportion of the Korean population would be covered by these cell lines in organ transplantation, 27 cell lines with HLA-A, -B, and -DR data were evaluated for HCT (cord blood) donors and 28 cell lines with HLA-DR and ABO data were evaluated for solid organ (kidney) transplantation donors, and then compared the data with those from 6,740 donated cord bloods. When 2 HLA mismatches are allowed for HCT, as currently accepted for cord blood transplantation, it was estimated that about 16% and 25% of the possible recipients can find one or more donor cell lines with ≤2 mismatches at A, B, DRB1 allele level and at A, B antigen/DRB1 allele level, respectively. When HLA-DR antigen level matching and ABO compatibility was considered for solid organ (kidney) transplantation, it was estimated that about 29% and 96% of the possible recipients can find one or more ABO-compatible donor cell lines with 0 and 1 DR mismatches, respectively. We provided the first report on the HLA and ABO genotypes of hESC lines, and estimated the degree of HLA and ABO matching in organ transplantation for the Korean population." @default.
• W2121051882 created "2016-06-24" @default.
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• W2121051882 date "2010-11-01" @default.
• W2121051882 modified "2023-10-11" @default.
• W2121051882 title "Evaluation of 28 Human Embryonic Stem Cell Lines for Use as Unrelated Donors in Stem Cell Therapy: Implications of HLA and ABO Genotypes" @default.
• W2121051882 cites W1599568627 @default.
• W2121051882 cites W1603639817 @default.
• W2121051882 cites W1965613868 @default.
• W2121051882 cites W1965866635 @default.
• W2121051882 cites W1970200774 @default.
• W2121051882 cites W1976737877 @default.
• W2121051882 cites W1978173381 @default.
• W2121051882 cites W1978590853 @default.
• W2121051882 cites W1978826106 @default.
• W2121051882 cites W1979776443 @default.
• W2121051882 cites W1986752909 @default.
• W2121051882 cites W1987388203 @default.
• W2121051882 cites W1993587284 @default.
• W2121051882 cites W1994758141 @default.
• W2121051882 cites W1998570216 @default.
• W2121051882 cites W2002179012 @default.
• W2121051882 cites W2005972147 @default.
• W2121051882 cites W2006712783 @default.
• W2121051882 cites W2010031978 @default.
• W2121051882 cites W2017069582 @default.
• W2121051882 cites W2025950643 @default.
• W2121051882 cites W2028273576 @default.
• W2121051882 cites W2029931933 @default.
• W2121051882 cites W2030800882 @default.
• W2121051882 cites W2037388456 @default.
• W2121051882 cites W2037672698 @default.
• W2121051882 cites W2038723730 @default.
• W2121051882 cites W2039551265 @default.
• W2121051882 cites W2039856043 @default.
• W2121051882 cites W2039998629 @default.
• W2121051882 cites W2042161977 @default.
• W2121051882 cites W2050689355 @default.
• W2121051882 cites W2053911973 @default.
• W2121051882 cites W2054721856 @default.
• W2121051882 cites W2058124288 @default.
• W2121051882 cites W2060419129 @default.
• W2121051882 cites W2061069485 @default.
• W2121051882 cites W2063843114 @default.
• W2121051882 cites W2068370578 @default.
• W2121051882 cites W2072239613 @default.
• W2121051882 cites W2076184598 @default.
• W2121051882 cites W2082019843 @default.
• W2121051882 cites W2086943348 @default.
• W2121051882 cites W2091790925 @default.
• W2121051882 cites W2093267077 @default.
• W2121051882 cites W2104027922 @default.
• W2121051882 cites W2106485710 @default.
• W2121051882 cites W2107085081 @default.
• W2121051882 cites W2110301828 @default.
• W2121051882 cites W2112485709 @default.
• W2121051882 cites W2117961192 @default.
• W2121051882 cites W2118554336 @default.
• W2121051882 cites W2119152414 @default.
• W2121051882 cites W2125987139 @default.
• W2121051882 cites W2129534940 @default.
• W2121051882 cites W2130198866 @default.
• W2121051882 cites W2130663466 @default.
• W2121051882 cites W2133014598 @default.
• W2121051882 cites W2133501984 @default.
• W2121051882 cites W2135067231 @default.
• W2121051882 cites W2138442302 @default.
• W2121051882 cites W2139133344 @default.
• W2121051882 cites W2147448492 @default.
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• W2121051882 cites W2157496367 @default.
• W2121051882 cites W2157645703 @default.
• W2121051882 cites W2160220798 @default.
• W2121051882 cites W2160266371 @default.
• W2121051882 cites W2168100563 @default.
• W2121051882 cites W2314814450 @default.
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• W2121051882 doi "https://doi.org/10.3727/096368910x513991" @default.
• W2121051882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20587141" @default.
• W2121051882 hasPublicationYear "2010" @default.
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