Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121057502> ?p ?o ?g. }
- W2121057502 endingPage "276" @default.
- W2121057502 startingPage "269" @default.
- W2121057502 abstract "The 190 kD human IQGAP1 protein, by virtue of its N-terminal calponin-homology domain, is found associated with the actin cytoskeleton, and is capable of cross-linking actin filaments. IQGAP1 complexes with several proteins, including the Rho family GTPases Cdc42 and Rac, as well as calmodulin. It was previously noted that one of the IQ motifs of IQGAP1 displays significant similarity to a myosin heavy chain IQ motif responsible for binding the calmodulin-related myosin essential light chain (ELC). Employing the yeast two-hybrid methodology as well as in vitro binding experiments, we present evidence that a truncated version of IQGAP1 can interact with the myosin ELC. This interaction may have significant consequences for various cellular processes that involve actomyosin contractility, and suggests that the biological targets of the ELC may not be restricted to the myosin heavy chain." @default.
- W2121057502 created "2016-06-24" @default.
- W2121057502 creator A5025068768 @default.
- W2121057502 creator A5039464042 @default.
- W2121057502 creator A5057052331 @default.
- W2121057502 date "1998-10-01" @default.
- W2121057502 modified "2023-10-16" @default.
- W2121057502 title "Binding of Myosin Essential Light Chain to the Cytoskeleton-Associated Protein IQGAP1" @default.
- W2121057502 cites W1496223818 @default.
- W2121057502 cites W1505317991 @default.
- W2121057502 cites W1508733727 @default.
- W2121057502 cites W1548084460 @default.
- W2121057502 cites W1551597777 @default.
- W2121057502 cites W1555846956 @default.
- W2121057502 cites W1567369841 @default.
- W2121057502 cites W1594921148 @default.
- W2121057502 cites W1821679912 @default.
- W2121057502 cites W1872338654 @default.
- W2121057502 cites W1881577780 @default.
- W2121057502 cites W1965608446 @default.
- W2121057502 cites W1967035448 @default.
- W2121057502 cites W1978577044 @default.
- W2121057502 cites W1979642960 @default.
- W2121057502 cites W1981289239 @default.
- W2121057502 cites W1981505264 @default.
- W2121057502 cites W1982722271 @default.
- W2121057502 cites W1991006980 @default.
- W2121057502 cites W1992274725 @default.
- W2121057502 cites W1995319149 @default.
- W2121057502 cites W1995758301 @default.
- W2121057502 cites W1997087774 @default.
- W2121057502 cites W1998507619 @default.
- W2121057502 cites W1998682793 @default.
- W2121057502 cites W1998734127 @default.
- W2121057502 cites W2004767153 @default.
- W2121057502 cites W2009623058 @default.
- W2121057502 cites W2010643736 @default.
- W2121057502 cites W2014428378 @default.
- W2121057502 cites W2015338902 @default.
- W2121057502 cites W2017886031 @default.
- W2121057502 cites W2017966653 @default.
- W2121057502 cites W2022643801 @default.
- W2121057502 cites W2027810531 @default.
- W2121057502 cites W2032295238 @default.
- W2121057502 cites W2032419047 @default.
- W2121057502 cites W2045425113 @default.
- W2121057502 cites W2049367666 @default.
- W2121057502 cites W2051165421 @default.
- W2121057502 cites W2052093902 @default.
- W2121057502 cites W2064778684 @default.
- W2121057502 cites W2065262403 @default.
- W2121057502 cites W2067599824 @default.
- W2121057502 cites W2072209379 @default.
- W2121057502 cites W2072410836 @default.
- W2121057502 cites W2077792958 @default.
- W2121057502 cites W2078131336 @default.
- W2121057502 cites W2078384542 @default.
- W2121057502 cites W2085002625 @default.
- W2121057502 cites W2090286778 @default.
- W2121057502 cites W2103638901 @default.
- W2121057502 cites W2114072064 @default.
- W2121057502 cites W2117551288 @default.
- W2121057502 cites W2117602236 @default.
- W2121057502 cites W2119903691 @default.
- W2121057502 cites W2120385383 @default.
- W2121057502 cites W2124608908 @default.
- W2121057502 cites W2124713665 @default.
- W2121057502 cites W2130616353 @default.
- W2121057502 cites W2132127260 @default.
- W2121057502 cites W2133852124 @default.
- W2121057502 cites W2134585254 @default.
- W2121057502 cites W2143763532 @default.
- W2121057502 cites W2146055738 @default.
- W2121057502 cites W2146318623 @default.
- W2121057502 cites W2150939373 @default.
- W2121057502 cites W2151029098 @default.
- W2121057502 cites W2164550657 @default.
- W2121057502 cites W2165083476 @default.
- W2121057502 cites W2166710017 @default.
- W2121057502 cites W2169757641 @default.
- W2121057502 cites W2176481193 @default.
- W2121057502 cites W2177733342 @default.
- W2121057502 cites W2226209910 @default.
- W2121057502 cites W4247508617 @default.
- W2121057502 doi "https://doi.org/10.1006/bbrc.1998.9371" @default.
- W2121057502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9790945" @default.
- W2121057502 hasPublicationYear "1998" @default.
- W2121057502 type Work @default.
- W2121057502 sameAs 2121057502 @default.
- W2121057502 citedByCount "54" @default.
- W2121057502 countsByYear W21210575022012 @default.
- W2121057502 countsByYear W21210575022013 @default.
- W2121057502 countsByYear W21210575022014 @default.
- W2121057502 countsByYear W21210575022015 @default.
- W2121057502 countsByYear W21210575022018 @default.
- W2121057502 countsByYear W21210575022019 @default.
- W2121057502 countsByYear W21210575022020 @default.
- W2121057502 countsByYear W21210575022021 @default.