FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121084562> ?p ?o ?g. }

• W2121084562 endingPage "568" @default.
• W2121084562 startingPage "555" @default.
• W2121084562 abstract "To investigate microsatellite instability (MSI) in radiation-induced murine tumours, its dependence on tissue (haemopoietic, intestinal, mammary, brain and skin) and radiation type.DNA from spontaneous, X-ray or neutron-induced mouse tumours were used in Polymerase Chain Reactions (PCR) with mono- or di-nucleotide repeat markers. Deviations from expected allele size caused by insertion/deletion events were assessed by capillary electrophoresis.Tumours showing MSI increased from 16% in spontaneously arising tumours to 23% (P = 0.014) in X-ray-induced tumours and rising again to 83% (P << 0.001) in neutron-induced tumours. X-ray-induced Acute Myeloid Leukaemias (AML) had a higher level of mono-nucleotide instability (45%) than di-nucleotide instability (37%). Fifty percent of neutron-induced tumours were classified as MSI-high for mono-nucleotide markers and 10% for di-nucleotide markers. Distribution of MSI varied in the different tumour types and did not appear random.Exposure to ionising radiation, especially neutrons, promotes the development of MSI in mouse tumours. MSI may therefore play a role in mouse radiation tumourigenesis, particularly following high Linear Energy Transfer (LET) exposures. MSI events, for a comparable panel of genome-wide markers in different tissue types, were not randomly distributed throughout the genome." @default.
• W2121084562 created "2016-06-24" @default.
• W2121084562 creator A5009997717 @default.
• W2121084562 creator A5011816309 @default.
• W2121084562 creator A5033913755 @default.
• W2121084562 creator A5043816407 @default.
• W2121084562 creator A5070316955 @default.
• W2121084562 creator A5081111677 @default.
• W2121084562 creator A5081529617 @default.
• W2121084562 creator A5083809986 @default.
• W2121084562 date "2010-06-15" @default.
• W2121084562 modified "2023-09-26" @default.
• W2121084562 title "Microsatellite instability in radiation-induced murine tumours; influence of tumour type and radiation quality" @default.
• W2121084562 cites W1822066427 @default.
• W2121084562 cites W1963516318 @default.
• W2121084562 cites W1967205646 @default.
• W2121084562 cites W1981763122 @default.
• W2121084562 cites W1982129441 @default.
• W2121084562 cites W1983686026 @default.
• W2121084562 cites W1987107448 @default.
• W2121084562 cites W2005958249 @default.
• W2121084562 cites W2007364588 @default.
• W2121084562 cites W2018816409 @default.
• W2121084562 cites W2027239369 @default.
• W2121084562 cites W2048852551 @default.
• W2121084562 cites W2050776751 @default.
• W2121084562 cites W2053666128 @default.
• W2121084562 cites W2055434292 @default.
• W2121084562 cites W2065770209 @default.
• W2121084562 cites W2071837862 @default.
• W2121084562 cites W2075240053 @default.
• W2121084562 cites W2077128928 @default.
• W2121084562 cites W2080644667 @default.
• W2121084562 cites W2084121244 @default.
• W2121084562 cites W2088489316 @default.
• W2121084562 cites W2092884985 @default.
• W2121084562 cites W2093997105 @default.
• W2121084562 cites W2102330794 @default.
• W2121084562 cites W2104818405 @default.
• W2121084562 cites W2109271488 @default.
• W2121084562 cites W2132798533 @default.
• W2121084562 cites W2140595098 @default.
• W2121084562 cites W2149707007 @default.
• W2121084562 cites W2160185049 @default.
• W2121084562 cites W2164061514 @default.
• W2121084562 cites W2165068523 @default.
• W2121084562 cites W2171787842 @default.
• W2121084562 cites W2327023992 @default.
• W2121084562 cites W2335127095 @default.
• W2121084562 cites W2344820924 @default.
• W2121084562 cites W2083819574 @default.
• W2121084562 doi "https://doi.org/10.3109/09553001003734600" @default.
• W2121084562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20545567" @default.
• W2121084562 hasPublicationYear "2010" @default.
• W2121084562 type Work @default.
• W2121084562 sameAs 2121084562 @default.
• W2121084562 citedByCount "14" @default.
• W2121084562 countsByYear W21210845622012 @default.
• W2121084562 countsByYear W21210845622013 @default.
• W2121084562 countsByYear W21210845622015 @default.
• W2121084562 countsByYear W21210845622016 @default.
• W2121084562 countsByYear W21210845622017 @default.
• W2121084562 countsByYear W21210845622019 @default.
• W2121084562 countsByYear W21210845622020 @default.
• W2121084562 crossrefType "journal-article" @default.
• W2121084562 hasAuthorship W2121084562A5009997717 @default.
• W2121084562 hasAuthorship W2121084562A5011816309 @default.
• W2121084562 hasAuthorship W2121084562A5033913755 @default.
• W2121084562 hasAuthorship W2121084562A5043816407 @default.
• W2121084562 hasAuthorship W2121084562A5070316955 @default.
• W2121084562 hasAuthorship W2121084562A5081111677 @default.
• W2121084562 hasAuthorship W2121084562A5081529617 @default.
• W2121084562 hasAuthorship W2121084562A5083809986 @default.
• W2121084562 hasConcept C104317684 @default.
• W2121084562 hasConcept C111337013 @default.
• W2121084562 hasConcept C114246631 @default.
• W2121084562 hasConcept C121332964 @default.
• W2121084562 hasConcept C143425029 @default.
• W2121084562 hasConcept C153911025 @default.
• W2121084562 hasConcept C178169997 @default.
• W2121084562 hasConcept C180754005 @default.
• W2121084562 hasConcept C18231593 @default.
• W2121084562 hasConcept C185544564 @default.
• W2121084562 hasConcept C2779767149 @default.
• W2121084562 hasConcept C502942594 @default.
• W2121084562 hasConcept C512185932 @default.
• W2121084562 hasConcept C54355233 @default.
• W2121084562 hasConcept C552990157 @default.
• W2121084562 hasConcept C61320498 @default.
• W2121084562 hasConcept C86803240 @default.
• W2121084562 hasConceptScore W2121084562C104317684 @default.
• W2121084562 hasConceptScore W2121084562C111337013 @default.
• W2121084562 hasConceptScore W2121084562C114246631 @default.
• W2121084562 hasConceptScore W2121084562C121332964 @default.
• W2121084562 hasConceptScore W2121084562C143425029 @default.
• W2121084562 hasConceptScore W2121084562C153911025 @default.
• W2121084562 hasConceptScore W2121084562C178169997 @default.
• W2121084562 hasConceptScore W2121084562C180754005 @default.

• next