Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121103048> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2121103048 endingPage "15" @default.
- W2121103048 startingPage "12" @default.
- W2121103048 abstract "INTRODUCTION: Hypothalamic hamartoma is a rare congenital malformation, characterized by epilepsy, especially gelastic seizures, psychomotor developmental delay, mental retardation, behavioral disorders and precocious puberty. Epilepsy has early onset and is usually medically refractory. Etiology and pathophysiological mechanisms are unclear. The EEG can present disorganization and slowing of background activity and multifocal and/or generalized epileptogenic discharges. OBJECTIVE: To report the difficulties and challenges of neurosurgical treatment of a hypothalamic hamartoma in an infant. CASE REPORT: Infant with seizures since eight months old of age. The neurological investigation revealed a lesion in tuber cinereum suggestive of hamartoma. The epilepsy evolved with resistance to antiepileptic drugs, requiring neurosurgical procedure. The endoscopic resection could not be performed because the hamartoma was firmly attached to the hypothalamus. Currently, the child remains with tonic, clonic and atonic seizures. DISCUSSION: Lesionectomy performed by microsurgery or radiosurgery seems to be the most effective treatment for seizure control in patients with hypothalamic hamartomas who do not respond to clinical treatment. Callosotomy may be effective in selected cases, and lobectomy/cortical resections are not related to seizure control. In some patients, particularly in infants, lesionectomy and radiosurgery may be technically unfeasible." @default.
- W2121103048 created "2016-06-24" @default.
- W2121103048 creator A5007225647 @default.
- W2121103048 creator A5053202629 @default.
- W2121103048 creator A5058998663 @default.
- W2121103048 creator A5068902965 @default.
- W2121103048 creator A5083590051 @default.
- W2121103048 date "2012-03-01" @default.
- W2121103048 modified "2023-09-27" @default.
- W2121103048 title "Challenges in the surgical treatment of epilepsy: hypothalamic hamartoma in infancy - case report" @default.
- W2121103048 cites W1965881853 @default.
- W2121103048 cites W2002735980 @default.
- W2121103048 cites W2022685966 @default.
- W2121103048 cites W2030168555 @default.
- W2121103048 cites W2083840314 @default.
- W2121103048 cites W2094474685 @default.
- W2121103048 cites W2116627975 @default.
- W2121103048 cites W2145074684 @default.
- W2121103048 cites W4236869319 @default.
- W2121103048 doi "https://doi.org/10.1590/s1676-26492012000100004" @default.
- W2121103048 hasPublicationYear "2012" @default.
- W2121103048 type Work @default.
- W2121103048 sameAs 2121103048 @default.
- W2121103048 citedByCount "1" @default.
- W2121103048 countsByYear W21211030482014 @default.
- W2121103048 crossrefType "journal-article" @default.
- W2121103048 hasAuthorship W2121103048A5007225647 @default.
- W2121103048 hasAuthorship W2121103048A5053202629 @default.
- W2121103048 hasAuthorship W2121103048A5058998663 @default.
- W2121103048 hasAuthorship W2121103048A5068902965 @default.
- W2121103048 hasAuthorship W2121103048A5083590051 @default.
- W2121103048 hasBestOaLocation W21211030481 @default.
- W2121103048 hasConcept C118552586 @default.
- W2121103048 hasConcept C126322002 @default.
- W2121103048 hasConcept C141071460 @default.
- W2121103048 hasConcept C142724271 @default.
- W2121103048 hasConcept C187212893 @default.
- W2121103048 hasConcept C2775932916 @default.
- W2121103048 hasConcept C2778186239 @default.
- W2121103048 hasConcept C2778367240 @default.
- W2121103048 hasConcept C2778815751 @default.
- W2121103048 hasConcept C2779449703 @default.
- W2121103048 hasConcept C2780387249 @default.
- W2121103048 hasConcept C2780803581 @default.
- W2121103048 hasConcept C2781156865 @default.
- W2121103048 hasConcept C2908900992 @default.
- W2121103048 hasConcept C509974204 @default.
- W2121103048 hasConcept C71315377 @default.
- W2121103048 hasConcept C71924100 @default.
- W2121103048 hasConceptScore W2121103048C118552586 @default.
- W2121103048 hasConceptScore W2121103048C126322002 @default.
- W2121103048 hasConceptScore W2121103048C141071460 @default.
- W2121103048 hasConceptScore W2121103048C142724271 @default.
- W2121103048 hasConceptScore W2121103048C187212893 @default.
- W2121103048 hasConceptScore W2121103048C2775932916 @default.
- W2121103048 hasConceptScore W2121103048C2778186239 @default.
- W2121103048 hasConceptScore W2121103048C2778367240 @default.
- W2121103048 hasConceptScore W2121103048C2778815751 @default.
- W2121103048 hasConceptScore W2121103048C2779449703 @default.
- W2121103048 hasConceptScore W2121103048C2780387249 @default.
- W2121103048 hasConceptScore W2121103048C2780803581 @default.
- W2121103048 hasConceptScore W2121103048C2781156865 @default.
- W2121103048 hasConceptScore W2121103048C2908900992 @default.
- W2121103048 hasConceptScore W2121103048C509974204 @default.
- W2121103048 hasConceptScore W2121103048C71315377 @default.
- W2121103048 hasConceptScore W2121103048C71924100 @default.
- W2121103048 hasIssue "1" @default.
- W2121103048 hasLocation W21211030481 @default.
- W2121103048 hasLocation W21211030482 @default.
- W2121103048 hasOpenAccess W2121103048 @default.
- W2121103048 hasPrimaryLocation W21211030481 @default.
- W2121103048 hasRelatedWork W106441133 @default.
- W2121103048 hasRelatedWork W1261767365 @default.
- W2121103048 hasRelatedWork W1885974868 @default.
- W2121103048 hasRelatedWork W1966538795 @default.
- W2121103048 hasRelatedWork W2048908268 @default.
- W2121103048 hasRelatedWork W2121103048 @default.
- W2121103048 hasRelatedWork W2189177734 @default.
- W2121103048 hasRelatedWork W2751474410 @default.
- W2121103048 hasRelatedWork W2796228083 @default.
- W2121103048 hasRelatedWork W3038157156 @default.
- W2121103048 hasVolume "18" @default.
- W2121103048 isParatext "false" @default.
- W2121103048 isRetracted "false" @default.
- W2121103048 magId "2121103048" @default.
- W2121103048 workType "article" @default.