FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121184758> ?p ?o ?g. }

• W2121184758 endingPage "262" @default.
• W2121184758 startingPage "247" @default.
• W2121184758 abstract "An elevation of natural killer (NK) cell activity was conditioned by the association of a camphor odor conditioning stimulus (CS) with an injection of 20 μg poly-inosinic:poly-cytidylic acid (poly I:C), the unconditioned stimulus (US). Poly I:C elicits the production and secretion of interferon (IFN), which induces an increase in NK cell activity. Reexposure to the CS occurred on Days 3 and 5 after the association trial on Day 0. Immediately following the CS exposure on Day 5, 1 μg poly I:C was administered to all animals. This procedure resulted in an increased NK cell activity in the conditioned (CND), but not the nonconditioned (NC), mice. In this study we have shown that the expression of the conditioned response was blocked by an injection of naltrexone (NTX) at 10 mg/kg ip when given immediately prior to the two test CS odor exposures. Peripheral treatment (ip) with a quaternary form of naltrexone (QNTX), which is a less potent opiate antagonist, at the same dose and at the same time relative to the CS odor reexposure did not block the conditioned response. The formation of the conditioned association did not appear to be disrupted by NTX at the 10 mg/kg dose when given immediately prior to the trial odor exposure on Day 0. No modulation of NK cell activity was observed in any of the control groups treated with naltrexone or the quaternary analog. Because of the inability of the QNTX to block the conditioned response, we hypothesize that the opiate receptors involved in the conditioned response and blocked by NTX were within the central nervous system (CNS). Whether this response is peripherally or centrally mediated, we have shown that opiate receptors represent part of the mechanism which mediates the conditioned augmentation of NK cell activity." @default.
• W2121184758 created "2016-06-24" @default.
• W2121184758 creator A5006252520 @default.
• W2121184758 creator A5025585907 @default.
• W2121184758 creator A5086421947 @default.
• W2121184758 date "1989-09-01" @default.
• W2121184758 modified "2023-09-26" @default.
• W2121184758 title "Naltrexone blocks the expression of the conditioned elevation of natural killer cell activity in BALBc mice" @default.
• W2121184758 cites W1509771501 @default.
• W2121184758 cites W1526366343 @default.
• W2121184758 cites W1550310038 @default.
• W2121184758 cites W1605641882 @default.
• W2121184758 cites W1670487437 @default.
• W2121184758 cites W1676250666 @default.
• W2121184758 cites W1967075968 @default.
• W2121184758 cites W1968299978 @default.
• W2121184758 cites W1971612269 @default.
• W2121184758 cites W1979734924 @default.
• W2121184758 cites W1981935824 @default.
• W2121184758 cites W1985663362 @default.
• W2121184758 cites W1988657646 @default.
• W2121184758 cites W1990209348 @default.
• W2121184758 cites W1993319836 @default.
• W2121184758 cites W1995877824 @default.
• W2121184758 cites W1997619239 @default.
• W2121184758 cites W2008680239 @default.
• W2121184758 cites W2021417075 @default.
• W2121184758 cites W2026378984 @default.
• W2121184758 cites W2026495673 @default.
• W2121184758 cites W2034530607 @default.
• W2121184758 cites W2038090777 @default.
• W2121184758 cites W2039245564 @default.
• W2121184758 cites W2044358712 @default.
• W2121184758 cites W2049659510 @default.
• W2121184758 cites W2050771836 @default.
• W2121184758 cites W2055407329 @default.
• W2121184758 cites W2080977352 @default.
• W2121184758 cites W2081691066 @default.
• W2121184758 cites W2083135448 @default.
• W2121184758 cites W2084881904 @default.
• W2121184758 cites W2087025176 @default.
• W2121184758 cites W2087188847 @default.
• W2121184758 cites W2092841670 @default.
• W2121184758 cites W2098345014 @default.
• W2121184758 cites W2107224500 @default.
• W2121184758 cites W2110337051 @default.
• W2121184758 cites W2125526579 @default.
• W2121184758 cites W2128003655 @default.
• W2121184758 cites W2154710740 @default.
• W2121184758 cites W4246563128 @default.
• W2121184758 doi "https://doi.org/10.1016/0889-1591(89)90040-8" @default.
• W2121184758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2482096" @default.
• W2121184758 hasPublicationYear "1989" @default.
• W2121184758 type Work @default.
• W2121184758 sameAs 2121184758 @default.
• W2121184758 citedByCount "29" @default.
• W2121184758 countsByYear W21211847582013 @default.
• W2121184758 crossrefType "journal-article" @default.
• W2121184758 hasAuthorship W2121184758A5006252520 @default.
• W2121184758 hasAuthorship W2121184758A5025585907 @default.
• W2121184758 hasAuthorship W2121184758A5086421947 @default.
• W2121184758 hasConcept C105795698 @default.
• W2121184758 hasConcept C126322002 @default.
• W2121184758 hasConcept C134018914 @default.
• W2121184758 hasConcept C170493617 @default.
• W2121184758 hasConcept C178790620 @default.
• W2121184758 hasConcept C185592680 @default.
• W2121184758 hasConcept C2776885963 @default.
• W2121184758 hasConcept C2777972943 @default.
• W2121184758 hasConcept C2778140631 @default.
• W2121184758 hasConcept C2778468042 @default.
• W2121184758 hasConcept C2778916471 @default.
• W2121184758 hasConcept C33923547 @default.
• W2121184758 hasConcept C39617858 @default.
• W2121184758 hasConcept C45262634 @default.
• W2121184758 hasConcept C71924100 @default.
• W2121184758 hasConcept C98274493 @default.
• W2121184758 hasConceptScore W2121184758C105795698 @default.
• W2121184758 hasConceptScore W2121184758C126322002 @default.
• W2121184758 hasConceptScore W2121184758C134018914 @default.
• W2121184758 hasConceptScore W2121184758C170493617 @default.
• W2121184758 hasConceptScore W2121184758C178790620 @default.
• W2121184758 hasConceptScore W2121184758C185592680 @default.
• W2121184758 hasConceptScore W2121184758C2776885963 @default.
• W2121184758 hasConceptScore W2121184758C2777972943 @default.
• W2121184758 hasConceptScore W2121184758C2778140631 @default.
• W2121184758 hasConceptScore W2121184758C2778468042 @default.
• W2121184758 hasConceptScore W2121184758C2778916471 @default.
• W2121184758 hasConceptScore W2121184758C33923547 @default.
• W2121184758 hasConceptScore W2121184758C39617858 @default.
• W2121184758 hasConceptScore W2121184758C45262634 @default.
• W2121184758 hasConceptScore W2121184758C71924100 @default.
• W2121184758 hasConceptScore W2121184758C98274493 @default.
• W2121184758 hasIssue "3" @default.
• W2121184758 hasLocation W21211847581 @default.
• W2121184758 hasLocation W21211847582 @default.
• W2121184758 hasOpenAccess W2121184758 @default.
• W2121184758 hasPrimaryLocation W21211847581 @default.

• next