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- W2121217100 abstract "Guineapigs were allocated to one of four diets (normal without aspirin, scorbutogenic without aspirin, normal with aspirin, or scorbutogenic with aspirin) for 2 weeks, since guineapigs usually become frankly scorbutic after a scorbutogenic diet for 3-4 weeks. The aim was to determine the influence of a subclinical scorbutic state on the gastric erosions provoked by aspirin. Guineapigs on the scorbutogenic diet bled from the gastric mucosa significantly more often than those on a normal diet. The addition of aspirin to a scorbutogenic diet significantly increased the likelihood of gastric mucosal bleeding. Aspirin thus seems to precipitate gastric mucosal hæmorrhage more readily when guineapigs are in a subclinical scorbutic condition. These results, taken in conjunction with the clinical findings described elsewhere, suggest that aspirin is more likely to cause significant gastric mucosal hæmorrhage when subclinical scurvy is present." @default.
- W2121217100 created "2016-06-24" @default.
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- W2121217100 date "1968-09-01" @default.
- W2121217100 modified "2023-09-27" @default.
- W2121217100 title "EFFECT OF ASPIRIN ON THE GASTRIC MUCOSA OF GUINEAPIGS ON A SCORBUTOGENIC DIET" @default.
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- W2121217100 doi "https://doi.org/10.1016/s0140-6736(68)90699-5" @default.
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