Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121255954> ?p ?o ?g. }
- W2121255954 endingPage "49" @default.
- W2121255954 startingPage "43" @default.
- W2121255954 abstract "OBJECTIVE: People with schizophrenia, schizoaffective disorder, and bipolar illness share clinical symptoms, biological findings, and genetic susceptibility. Diminished suppression of the P50 auditory evoked potential is a phenotype used in studies of genetic susceptibility in schizophrenia. In patients with acute mania, this inhibitory deficit has been correlated with severity of clinical symptoms. This study addresses whether diminished P50 auditory evoked potential suppression represents a phenotype associated with psychosis in bipolar illness. METHOD: The P50 auditory evoked potential response to paired stimuli was measured in 64 subjects with bipolar illness. The Structured Clinical Interview for DSM-IV and a life chart determined diagnosis. The Beck Depression Inventory, Young Mania Rating Scale, and the Positive and Negative Syndrome Scale measured severity of current illness. Groups were compared with previously collected data from 36 schizophrenia patients and 42 healthy subjects. RESULTS: P50 suppression significantly differed between bipolar disorder patients with a lifetime history of psychosis and healthy subjects. P50 suppression in bipolar disorder patients without a history of psychosis did not differ from that of the healthy subjects. Severity of current symptoms did not correlate with P50 suppression. CONCLUSIONS: A longitudinal history of psychosis in subjects with bipolar illness was associated with diminished suppression of the P50 auditory evoked potential. This deficit may represent a common physiological mechanism associated with the vulnerability to psychosis in people with bipolar illness as well as in people with schizophrenia." @default.
- W2121255954 created "2016-06-24" @default.
- W2121255954 creator A5027460018 @default.
- W2121255954 creator A5067292698 @default.
- W2121255954 date "2005-01-01" @default.
- W2121255954 modified "2023-10-16" @default.
- W2121255954 title "Diminished Suppression of the P50 Auditory Evoked Potential in Bipolar Disorder Subjects With a History of Psychosis" @default.
- W2121255954 cites W152718690 @default.
- W2121255954 cites W1532317254 @default.
- W2121255954 cites W172603261 @default.
- W2121255954 cites W1968524760 @default.
- W2121255954 cites W1980215843 @default.
- W2121255954 cites W1983569704 @default.
- W2121255954 cites W1988281657 @default.
- W2121255954 cites W1996605747 @default.
- W2121255954 cites W1996669209 @default.
- W2121255954 cites W1999225329 @default.
- W2121255954 cites W2006185528 @default.
- W2121255954 cites W2007986510 @default.
- W2121255954 cites W2008300370 @default.
- W2121255954 cites W201751606 @default.
- W2121255954 cites W2024539842 @default.
- W2121255954 cites W2028572307 @default.
- W2121255954 cites W2029747200 @default.
- W2121255954 cites W2031994637 @default.
- W2121255954 cites W2044557200 @default.
- W2121255954 cites W2051647982 @default.
- W2121255954 cites W2051806956 @default.
- W2121255954 cites W2060474957 @default.
- W2121255954 cites W2067362918 @default.
- W2121255954 cites W2067495470 @default.
- W2121255954 cites W2076400560 @default.
- W2121255954 cites W2076808939 @default.
- W2121255954 cites W2077822166 @default.
- W2121255954 cites W2079491808 @default.
- W2121255954 cites W2079946586 @default.
- W2121255954 cites W2086020244 @default.
- W2121255954 cites W2091792107 @default.
- W2121255954 cites W2094630986 @default.
- W2121255954 cites W2101194137 @default.
- W2121255954 cites W2107164282 @default.
- W2121255954 cites W2121985921 @default.
- W2121255954 cites W2122450421 @default.
- W2121255954 cites W2130630697 @default.
- W2121255954 cites W2140606211 @default.
- W2121255954 cites W2144430053 @default.
- W2121255954 cites W2147804098 @default.
- W2121255954 cites W2167659819 @default.
- W2121255954 cites W2170603069 @default.
- W2121255954 cites W2325997522 @default.
- W2121255954 cites W2331232937 @default.
- W2121255954 cites W2399442068 @default.
- W2121255954 cites W2444517157 @default.
- W2121255954 cites W3146425672 @default.
- W2121255954 cites W1672645577 @default.
- W2121255954 cites W2095409179 @default.
- W2121255954 doi "https://doi.org/10.1176/appi.ajp.162.1.43" @default.
- W2121255954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15625200" @default.
- W2121255954 hasPublicationYear "2005" @default.
- W2121255954 type Work @default.
- W2121255954 sameAs 2121255954 @default.
- W2121255954 citedByCount "143" @default.
- W2121255954 countsByYear W21212559542012 @default.
- W2121255954 countsByYear W21212559542013 @default.
- W2121255954 countsByYear W21212559542014 @default.
- W2121255954 countsByYear W21212559542015 @default.
- W2121255954 countsByYear W21212559542016 @default.
- W2121255954 countsByYear W21212559542017 @default.
- W2121255954 countsByYear W21212559542018 @default.
- W2121255954 countsByYear W21212559542019 @default.
- W2121255954 countsByYear W21212559542020 @default.
- W2121255954 countsByYear W21212559542021 @default.
- W2121255954 countsByYear W21212559542022 @default.
- W2121255954 countsByYear W21212559542023 @default.
- W2121255954 crossrefType "journal-article" @default.
- W2121255954 hasAuthorship W2121255954A5027460018 @default.
- W2121255954 hasAuthorship W2121255954A5067292698 @default.
- W2121255954 hasConcept C118552586 @default.
- W2121255954 hasConcept C126322002 @default.
- W2121255954 hasConcept C15744967 @default.
- W2121255954 hasConcept C2776174506 @default.
- W2121255954 hasConcept C2776412080 @default.
- W2121255954 hasConcept C2776809841 @default.
- W2121255954 hasConcept C2777089681 @default.
- W2121255954 hasConcept C2778528637 @default.
- W2121255954 hasConcept C2778609679 @default.
- W2121255954 hasConcept C2779727114 @default.
- W2121255954 hasConcept C2780325297 @default.
- W2121255954 hasConcept C2780733359 @default.
- W2121255954 hasConcept C2781179581 @default.
- W2121255954 hasConcept C2910604615 @default.
- W2121255954 hasConcept C71924100 @default.
- W2121255954 hasConceptScore W2121255954C118552586 @default.
- W2121255954 hasConceptScore W2121255954C126322002 @default.
- W2121255954 hasConceptScore W2121255954C15744967 @default.
- W2121255954 hasConceptScore W2121255954C2776174506 @default.
- W2121255954 hasConceptScore W2121255954C2776412080 @default.
- W2121255954 hasConceptScore W2121255954C2776809841 @default.