FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121320741> ?p ?o ?g. }

• W2121320741 endingPage "415" @default.
• W2121320741 startingPage "405" @default.
• W2121320741 abstract "The clinical significance of biochemical markers of myocardial damage or inflammation has not been prospectively established in populations representing the whole spectrum of acute coronary syndromes. We investigated whether the elevation of these biomarkers at admission has a prognostic value that is independent and incremental to baseline clinical variables and quantitative electrocardiographic ischemia.We measured blood levels of cardiac troponin I (cTnI) and C-reactive protein (CRP) in 1773 consecutive patients admitted to 31 Italian coronary care units within 12 hours from an episode of acute coronary syndrome. Primary and secondary outcomes were (1) 30-day incidence of death or nonfatal (re)infarction and (2) death alone.In a multivariate model, cTnI was independently associated with the risk of death or (re)infarction (OR, 1.8; 95% CI, 1.2 to 2.6; P =.002) and death (OR, 2.2; 95% CI, 1.4 to 3.4; P <.001), whereas CRP was of borderline significance for the primary outcome but was associated with death (OR, 1.4; 95% CI, 1.0 to 2.1; P =.06, and OR, 1.7; 95% CI, 1.1 to 2.6; P =.01, respectively). However, the inclusion of the biomarkers did not increase the prognostic capacity of the clinical risk model (C-index of both models with and without biomarkers was 0.73 for the primary outcome measures and 0.80 for the secondary outcome measures). CRP further stratified cTnI-negative patients. The prognostic significance of the biomarkers was similar in patients with and in those without persistent ST-segment elevation.In acute coronary syndromes, the elevation of cTnI and CRP at admission has an independent prognostic value that is not incremental to baseline clinical variables and quantitative electrocardiographic ischemia." @default.
• W2121320741 created "2016-06-24" @default.
• W2121320741 creator A5007381517 @default.
• W2121320741 creator A5032158326 @default.
• W2121320741 creator A5074896023 @default.
• W2121320741 date "2004-09-01" @default.
• W2121320741 modified "2023-10-16" @default.
• W2121320741 title "Clinical significance of a single measurement of troponin-I and C-reactive protein at admission in 1773 consecutive patients with acute coronary syndromes" @default.
• W2121320741 cites W1540428586 @default.
• W2121320741 cites W1946194227 @default.
• W2121320741 cites W1974424887 @default.
• W2121320741 cites W2009741254 @default.
• W2121320741 cites W2020915677 @default.
• W2121320741 cites W2028652089 @default.
• W2121320741 cites W2030884106 @default.
• W2121320741 cites W2034690624 @default.
• W2121320741 cites W2056495130 @default.
• W2121320741 cites W2080366036 @default.
• W2121320741 cites W2089865619 @default.
• W2121320741 cites W2093242089 @default.
• W2121320741 cites W2094378037 @default.
• W2121320741 cites W2115082047 @default.
• W2121320741 cites W2121495229 @default.
• W2121320741 cites W2124724401 @default.
• W2121320741 cites W2130978885 @default.
• W2121320741 cites W2146163621 @default.
• W2121320741 cites W2158336299 @default.
• W2121320741 cites W2159121887 @default.
• W2121320741 cites W2171747936 @default.
• W2121320741 cites W2313159400 @default.
• W2121320741 cites W2315575691 @default.
• W2121320741 cites W2327567334 @default.
• W2121320741 cites W2338764889 @default.
• W2121320741 cites W3007879772 @default.
• W2121320741 cites W4232161516 @default.
• W2121320741 doi "https://doi.org/10.1016/j.ahj.2004.03.023" @default.
• W2121320741 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15389226" @default.
• W2121320741 hasPublicationYear "2004" @default.
• W2121320741 type Work @default.
• W2121320741 sameAs 2121320741 @default.
• W2121320741 citedByCount "31" @default.
• W2121320741 countsByYear W21213207412012 @default.
• W2121320741 countsByYear W21213207412020 @default.
• W2121320741 countsByYear W21213207412021 @default.
• W2121320741 crossrefType "journal-article" @default.
• W2121320741 hasAuthorship W2121320741A5007381517 @default.
• W2121320741 hasAuthorship W2121320741A5032158326 @default.
• W2121320741 hasAuthorship W2121320741A5074896023 @default.
• W2121320741 hasConcept C115725540 @default.
• W2121320741 hasConcept C126322002 @default.
• W2121320741 hasConcept C164705383 @default.
• W2121320741 hasConcept C2776914184 @default.
• W2121320741 hasConcept C2777698277 @default.
• W2121320741 hasConcept C2781195455 @default.
• W2121320741 hasConcept C36036425 @default.
• W2121320741 hasConcept C500558357 @default.
• W2121320741 hasConcept C63363279 @default.
• W2121320741 hasConcept C71924100 @default.
• W2121320741 hasConceptScore W2121320741C115725540 @default.
• W2121320741 hasConceptScore W2121320741C126322002 @default.
• W2121320741 hasConceptScore W2121320741C164705383 @default.
• W2121320741 hasConceptScore W2121320741C2776914184 @default.
• W2121320741 hasConceptScore W2121320741C2777698277 @default.
• W2121320741 hasConceptScore W2121320741C2781195455 @default.
• W2121320741 hasConceptScore W2121320741C36036425 @default.
• W2121320741 hasConceptScore W2121320741C500558357 @default.
• W2121320741 hasConceptScore W2121320741C63363279 @default.
• W2121320741 hasConceptScore W2121320741C71924100 @default.
• W2121320741 hasIssue "3" @default.
• W2121320741 hasLocation W21213207411 @default.
• W2121320741 hasLocation W21213207412 @default.
• W2121320741 hasOpenAccess W2121320741 @default.
• W2121320741 hasPrimaryLocation W21213207411 @default.
• W2121320741 hasRelatedWork W2038028974 @default.
• W2121320741 hasRelatedWork W2054023746 @default.
• W2121320741 hasRelatedWork W2150800341 @default.
• W2121320741 hasRelatedWork W2361553567 @default.
• W2121320741 hasRelatedWork W2375621908 @default.
• W2121320741 hasRelatedWork W2381008758 @default.
• W2121320741 hasRelatedWork W2385463368 @default.
• W2121320741 hasRelatedWork W3008078763 @default.
• W2121320741 hasRelatedWork W593240835 @default.
• W2121320741 hasRelatedWork W88721532 @default.
• W2121320741 hasVolume "148" @default.
• W2121320741 isParatext "false" @default.
• W2121320741 isRetracted "false" @default.
• W2121320741 magId "2121320741" @default.
• W2121320741 workType "article" @default.