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- W2121372323 abstract "Selected cationic and anionic surface-active compounds were tested to determine their virucidal effect on the foot-and-mouth disease virus, type O, strain M11, propagated in primary calf kidney cells. The chemical inactivation of the virus was tested with 0.5, 1.0, 2.0, and 5.0% concentrations of the selected compounds. Virus controls with p H adjusted to cover the expected range of the mixtures of the chemicals and virus were also tested. The absence of virus from the mixtures of chemical and virus after reaction at 28 C for 2 hr was assayed by inoculating suckling mice with the mixtures. One cationic compound, alkyl methyl isoquinilinium chloride, showed considerable antiviral activity due largely to p H effect. The use of the surface-active agents investigated in this study, in the presence of organic material, would not be recommended as virucides." @default.
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- W2121372323 date "1965-09-01" @default.
- W2121372323 modified "2023-09-23" @default.
- W2121372323 title "Some Surface-Active Agents and Their Virucidal Effect on Foot-and-Mouth Disease Virus" @default.
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- W2121372323 doi "https://doi.org/10.1128/am.13.5.694-697.1965" @default.
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