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- W2121401815 abstract "Tumour angiogenesis allows a growing mass of cancer cells to overcome oxygen diffusion limitation and to increase cell survival. The growth of capillaries from pre-existing blood vessels is the result of numerous signalling cascades involving different molecules and of cellular events involving multiple cell and tissue types. Computational models offer insight into the mechanisms governing angiogenesis and provide quantitative information on parameters difficult to assess by experiments alone. In this article, we summarize results from computational models of tumour angiogenic processes with a focus on the molecular-detailed vascular endothelial growth factor-associated models that have been developed in our laboratory, spanning multiple scales from the molecular to whole body." @default.
- W2121401815 created "2016-06-24" @default.
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- W2121401815 date "2011-01-25" @default.
- W2121401815 modified "2023-10-14" @default.
- W2121401815 title "Computational models of VEGF-associated angiogenic processes in cancer" @default.
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- W2121401815 doi "https://doi.org/10.1093/imammb/dqq025" @default.
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