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- W2121426763 abstract "<b>Background:</b> The establishment and maintenance of oral microbiota is related not only to interbacterial coaggregations but also to interactions of these bacteria with yeasts<i>.</i> Hence, it is important for agents used in the treatment of oral diseases to have antifungal properties for effective therapy.<br> <b>Objective:</b> The main purpose of this study was to evaluate the <i>in vitro</i> antifungal efficacy of <i>Punica granatum, Acacia nilotica, Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans.</i><br> <b>Materials and Methods:</b> The pomegranate peel is separated, dried and powdered. Fennel, cumin and acacia bark obtained from the tree are powdered. Candida is inoculated at 37˚C and seeded on Sabourauds agar medium. Sterilized filter papers saturated with 30 μl of the<u>th</u> extracts are placed on the seeded plates and inoculated at 24 and 48 h. Zones of inhibition on all four sides are measured around the filter paper with a vernier caliper. The experiments were repeated on four plates, with four samples of each extract on one plate for all of the extracts.<br> <b>Results:</b> All the above-mentioned ingredients showed antifungal property, with <i>Punica granatum</i> showing the highest inhibition of <i>Candida albicans</i> with a mean zone of inhibition of 22 mm. <i>P</i>-values <0.05 were obtained for <i>Punica granatum</i> when compared with the other extracts.<br><b>Conclusion:</b> The results showed the potential use of these products as cheap and convenient adjuvants to pharmaceutical antifungal products." @default.
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- W2121426763 date "2010-01-01" @default.
- W2121426763 modified "2023-10-11" @default.
- W2121426763 title "Antifungal efficacy of Punica granatum, Acacia nilotica, Cuminum cyminum and Foeniculum vulgare on Candida albicans: An in vitro study" @default.
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- W2121426763 doi "https://doi.org/10.4103/0970-9290.70792" @default.
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