FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121453301> ?p ?o ?g. }

• W2121453301 endingPage "12" @default.
• W2121453301 startingPage "4" @default.
• W2121453301 abstract "Improving fat absorption remains a challenge in cystic fibrosis (CF). Antibiotics (AB) treatment has been shown to improve body weight in CF mice. The mechanism may include improvement in fat absorption. We aimed to determine the effect of AB on fat absorption in two CF mouse models.AB did not improve total fat absorption. Interestingly, AB accelerated the absorption of isotope-labeled fats, in both Δ/Δ and WT mice. The changes observed were not related to the solubilization capacity of bile or to changes in the bacteria in the small intestine. AB reduced the fecal excretion of cholate by ~50% (P < 0.05) in both CF mouse models, indicating improved intestinal bile salt absorption.In conclusion, AB treatment does not improve total fat absorption in CF mice but does decrease fecal loss of bile salts and accelerate long-chain fatty acid (LCFA) absorption.For 3 weeks, we administered oral AB (ciprofloxacin/metronidazole) or control treatment to homozygous ΔF508 (Δ/Δ), cystic fibrosis transmembrane conductance regulator (CFTR) knockout (-/-), and wild-type (WT) mice and quantified fat absorption using a 72-h fat balance test. In Δ/Δ mice, we assessed fat absorption kinetics by administering tri-1-(13)C-palmitin and 1-(13)C-stearate intragastrically and determining the appearance of stable isotope-labeled fats in plasma. We quantified biliary and fecal bile salts (gas chromatography) and small intestinal bacteria (quantitative-PCR)." @default.
• W2121453301 created "2016-06-24" @default.
• W2121453301 creator A5011298606 @default.
• W2121453301 creator A5023055657 @default.
• W2121453301 creator A5031718124 @default.
• W2121453301 creator A5038163774 @default.
• W2121453301 creator A5043109979 @default.
• W2121453301 creator A5087129912 @default.
• W2121453301 date "2011-12-15" @default.
• W2121453301 modified "2023-09-26" @default.
• W2121453301 title "Effect of antibiotic treatment on fat absorption in mice with cystic fibrosis" @default.
• W2121453301 cites W1745058254 @default.
• W2121453301 cites W1943976550 @default.
• W2121453301 cites W1966202035 @default.
• W2121453301 cites W1976791053 @default.
• W2121453301 cites W1977909276 @default.
• W2121453301 cites W1989830604 @default.
• W2121453301 cites W1998089326 @default.
• W2121453301 cites W2034568358 @default.
• W2121453301 cites W2037635161 @default.
• W2121453301 cites W2042761114 @default.
• W2121453301 cites W2045869506 @default.
• W2121453301 cites W2069736778 @default.
• W2121453301 cites W2070459632 @default.
• W2121453301 cites W2088155518 @default.
• W2121453301 cites W2090648579 @default.
• W2121453301 cites W2097796797 @default.
• W2121453301 cites W2109329073 @default.
• W2121453301 cites W2116071769 @default.
• W2121453301 cites W2128677706 @default.
• W2121453301 cites W2130824853 @default.
• W2121453301 cites W2133931920 @default.
• W2121453301 cites W2141311686 @default.
• W2121453301 cites W2148066964 @default.
• W2121453301 cites W2149910398 @default.
• W2121453301 cites W2153131048 @default.
• W2121453301 cites W2170363361 @default.
• W2121453301 doi "https://doi.org/10.1038/pr.2011.4" @default.
• W2121453301 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3786567" @default.
• W2121453301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22289844" @default.
• W2121453301 hasPublicationYear "2011" @default.
• W2121453301 type Work @default.
• W2121453301 sameAs 2121453301 @default.
• W2121453301 citedByCount "10" @default.
• W2121453301 countsByYear W21214533012012 @default.
• W2121453301 countsByYear W21214533012013 @default.
• W2121453301 countsByYear W21214533012015 @default.
• W2121453301 countsByYear W21214533012017 @default.
• W2121453301 countsByYear W21214533012019 @default.
• W2121453301 countsByYear W21214533012020 @default.
• W2121453301 crossrefType "journal-article" @default.
• W2121453301 hasAuthorship W2121453301A5011298606 @default.
• W2121453301 hasAuthorship W2121453301A5023055657 @default.
• W2121453301 hasAuthorship W2121453301A5031718124 @default.
• W2121453301 hasAuthorship W2121453301A5038163774 @default.
• W2121453301 hasAuthorship W2121453301A5043109979 @default.
• W2121453301 hasAuthorship W2121453301A5087129912 @default.
• W2121453301 hasBestOaLocation W21214533011 @default.
• W2121453301 hasConcept C10146269 @default.
• W2121453301 hasConcept C121332964 @default.
• W2121453301 hasConcept C125287762 @default.
• W2121453301 hasConcept C126322002 @default.
• W2121453301 hasConcept C134018914 @default.
• W2121453301 hasConcept C185592680 @default.
• W2121453301 hasConcept C24890656 @default.
• W2121453301 hasConcept C2775900799 @default.
• W2121453301 hasConcept C2776938444 @default.
• W2121453301 hasConcept C2777675875 @default.
• W2121453301 hasConcept C2777882243 @default.
• W2121453301 hasConcept C2778428886 @default.
• W2121453301 hasConcept C2779399885 @default.
• W2121453301 hasConcept C55493867 @default.
• W2121453301 hasConcept C61716771 @default.
• W2121453301 hasConcept C71924100 @default.
• W2121453301 hasConcept C86803240 @default.
• W2121453301 hasConcept C89423630 @default.
• W2121453301 hasConceptScore W2121453301C10146269 @default.
• W2121453301 hasConceptScore W2121453301C121332964 @default.
• W2121453301 hasConceptScore W2121453301C125287762 @default.
• W2121453301 hasConceptScore W2121453301C126322002 @default.
• W2121453301 hasConceptScore W2121453301C134018914 @default.
• W2121453301 hasConceptScore W2121453301C185592680 @default.
• W2121453301 hasConceptScore W2121453301C24890656 @default.
• W2121453301 hasConceptScore W2121453301C2775900799 @default.
• W2121453301 hasConceptScore W2121453301C2776938444 @default.
• W2121453301 hasConceptScore W2121453301C2777675875 @default.
• W2121453301 hasConceptScore W2121453301C2777882243 @default.
• W2121453301 hasConceptScore W2121453301C2778428886 @default.
• W2121453301 hasConceptScore W2121453301C2779399885 @default.
• W2121453301 hasConceptScore W2121453301C55493867 @default.
• W2121453301 hasConceptScore W2121453301C61716771 @default.
• W2121453301 hasConceptScore W2121453301C71924100 @default.
• W2121453301 hasConceptScore W2121453301C86803240 @default.
• W2121453301 hasConceptScore W2121453301C89423630 @default.
• W2121453301 hasIssue "1" @default.
• W2121453301 hasLocation W21214533011 @default.
• W2121453301 hasLocation W21214533012 @default.
• W2121453301 hasLocation W21214533013 @default.

• next