Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121465753> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2121465753 endingPage "419" @default.
- W2121465753 startingPage "411" @default.
- W2121465753 abstract "SUMMARY: Growth of a biotin-requiring strain of Saccharomyces cerevisiae in a medium containing a suboptimal concentration of biotin caused changes in the fine structure of the yeast as revealed by electron microscopy. The cytoplasmic and vacuolar membranes in yeast grown in unsupplemented biotin-deficient medium were particularly susceptible to polymerization damage and appeared to split along the lipid layer. Similar changes in the appearance of the cytoplasmic membrane were observed in biotin-optimal yeast after treatment with aqueous butanol. Yeast grown in unsupplemented biotin-deficient medium also contained a slightly greater number of large storage granules as compared with exponential phase biotinoptimal yeast. When grown in aspartate-supplemented biotin-deficient medium, the yeast had much thicker cell walls than when grown in unsupplemented biotin-deficient medium. In yeast grown in oleate-supplemented biotin-deficient medium, the cytoplasmic membrane split less extensively along the lipid layer as compared with yeast grown in unsupplemented biotin-deficient medium. Organisms grown in biotin-deficient medium supplemented with aspartate + oleate resembled those grown in biotin-deficient medium supplemented with only aspartate in possessing thick cell walls, but otherwise were similar in fine structure to yeast grown in oleate-supplemented biotin-deficient medium. The storage granules in yeast grown in biotin-optimal medium and in unsupplemented biotin-deficient medium stained strongly with Sudan Black B, a lipophilic stain, and their appearance in increased numbers in yeast grown in unsupplemented biotin-deficient medium was accompanied by an increase in the lipid content of the yeast as compared with biotin-optimal yeast. The significance of these changes in fine structure is discussed in relation to changes in chemical composition previously reported to result from an imposition of biotin deficiency in the yeast." @default.
- W2121465753 created "2016-06-24" @default.
- W2121465753 creator A5033123185 @default.
- W2121465753 creator A5072494452 @default.
- W2121465753 date "1964-06-01" @default.
- W2121465753 modified "2023-09-23" @default.
- W2121465753 title "Observations on the Fine Structure of Saccharomyces cerevisiae as Affected by Biotin Deficiency" @default.
- W2121465753 cites W1596927335 @default.
- W2121465753 cites W2007813081 @default.
- W2121465753 cites W2012061107 @default.
- W2121465753 cites W2014097105 @default.
- W2121465753 cites W2016199394 @default.
- W2121465753 cites W2059601322 @default.
- W2121465753 doi "https://doi.org/10.1099/00221287-35-3-411" @default.
- W2121465753 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14188768" @default.
- W2121465753 hasPublicationYear "1964" @default.
- W2121465753 type Work @default.
- W2121465753 sameAs 2121465753 @default.
- W2121465753 citedByCount "24" @default.
- W2121465753 countsByYear W21214657532014 @default.
- W2121465753 countsByYear W21214657532021 @default.
- W2121465753 crossrefType "journal-article" @default.
- W2121465753 hasAuthorship W2121465753A5033123185 @default.
- W2121465753 hasAuthorship W2121465753A5072494452 @default.
- W2121465753 hasBestOaLocation W21214657531 @default.
- W2121465753 hasConcept C185592680 @default.
- W2121465753 hasConcept C2776294945 @default.
- W2121465753 hasConcept C2777576037 @default.
- W2121465753 hasConcept C2778204606 @default.
- W2121465753 hasConcept C2779222958 @default.
- W2121465753 hasConcept C2780919596 @default.
- W2121465753 hasConcept C523546767 @default.
- W2121465753 hasConcept C54355233 @default.
- W2121465753 hasConcept C55493867 @default.
- W2121465753 hasConcept C86803240 @default.
- W2121465753 hasConceptScore W2121465753C185592680 @default.
- W2121465753 hasConceptScore W2121465753C2776294945 @default.
- W2121465753 hasConceptScore W2121465753C2777576037 @default.
- W2121465753 hasConceptScore W2121465753C2778204606 @default.
- W2121465753 hasConceptScore W2121465753C2779222958 @default.
- W2121465753 hasConceptScore W2121465753C2780919596 @default.
- W2121465753 hasConceptScore W2121465753C523546767 @default.
- W2121465753 hasConceptScore W2121465753C54355233 @default.
- W2121465753 hasConceptScore W2121465753C55493867 @default.
- W2121465753 hasConceptScore W2121465753C86803240 @default.
- W2121465753 hasIssue "3" @default.
- W2121465753 hasLocation W21214657531 @default.
- W2121465753 hasLocation W21214657532 @default.
- W2121465753 hasOpenAccess W2121465753 @default.
- W2121465753 hasPrimaryLocation W21214657531 @default.
- W2121465753 hasRelatedWork W1562086046 @default.
- W2121465753 hasRelatedWork W2007813081 @default.
- W2121465753 hasRelatedWork W2009810460 @default.
- W2121465753 hasRelatedWork W2026244176 @default.
- W2121465753 hasRelatedWork W2061541440 @default.
- W2121465753 hasRelatedWork W2062385823 @default.
- W2121465753 hasRelatedWork W2064741376 @default.
- W2121465753 hasRelatedWork W2084823085 @default.
- W2121465753 hasRelatedWork W2087346710 @default.
- W2121465753 hasRelatedWork W2121465753 @default.
- W2121465753 hasVolume "35" @default.
- W2121465753 isParatext "false" @default.
- W2121465753 isRetracted "false" @default.
- W2121465753 magId "2121465753" @default.
- W2121465753 workType "article" @default.