FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121498623> ?p ?o ?g. }

• W2121498623 endingPage "912" @default.
• W2121498623 startingPage "899" @default.
• W2121498623 abstract "The aim of the present article is to evaluate critically the various methods employed in studies designed to quantify precisely skeletal muscle substrate utilization during exercise. In general, the pattern of substrate utilization during exercise can be described well from O2 uptake measurements and the respiratory exchange ratio. However, if the aim is to quantify limb or muscle metabolism, invasive measurements have to be carried out, such as the determination of blood flow, arterio-venous (a-v) difference measurements for O2 and relevant substrates, and biopsies of the active muscle. As many substrates and metabolites may be both taken up and released by muscle at rest and during exercise, isotopes can be used to determine uptake and/or release and also fractional uptake can be accounted for. Furthermore, the use of isotopes opens up further possibilities for the estimation of oxidation rates of various substrates. There are several methodological concerns to be aware of when studying the metabolic response to exercise in human subjects. These concerns include: (1) the muscle mass involved in the exercise is largely unknown (bicycle or treadmill). Moreover, whether the muscle sample obtained from a limb muscle and the substrate and metabolite concentrations are representative can be a problem; (2) the placement of the venous catheter can be critical, and it should be secured so that the blood sample represents blood from the active muscle with a minimum of contamination from other muscles and tissues; (3) the use of net limb glycerol release to estimate lipolysis is probably not valid (triacylglycerol utilization by muscle), since glycerol can be metabolized in skeletal muscle; (4) the precision of blood-borne substrate concentrations during exercise measured by a-v difference is hampered since they become very small due to the high blood flow. Recommendations are given in order to obtain more quantitative and conclusive data in studies investigating the regulatory mechanisms for substrate choice by muscle." @default.
• W2121498623 created "2016-06-24" @default.
• W2121498623 creator A5015138528 @default.
• W2121498623 creator A5040925170 @default.
• W2121498623 creator A5060775202 @default.
• W2121498623 creator A5084806864 @default.
• W2121498623 date "1999-11-01" @default.
• W2121498623 modified "2023-10-17" @default.
• W2121498623 title "Skeletal muscle substrate metabolism during exercise: methodological considerations" @default.
• W2121498623 cites W1417669828 @default.
• W2121498623 cites W162965640 @default.
• W2121498623 cites W166961594 @default.
• W2121498623 cites W1973509065 @default.
• W2121498623 cites W1975308862 @default.
• W2121498623 cites W1975479485 @default.
• W2121498623 cites W1978495288 @default.
• W2121498623 cites W1981117508 @default.
• W2121498623 cites W1982728507 @default.
• W2121498623 cites W1989046922 @default.
• W2121498623 cites W1999853562 @default.
• W2121498623 cites W2000799758 @default.
• W2121498623 cites W2008323463 @default.
• W2121498623 cites W2010261383 @default.
• W2121498623 cites W2011985622 @default.
• W2121498623 cites W2029499765 @default.
• W2121498623 cites W2037453345 @default.
• W2121498623 cites W2039683004 @default.
• W2121498623 cites W2045836006 @default.
• W2121498623 cites W2051031292 @default.
• W2121498623 cites W2057127647 @default.
• W2121498623 cites W2059186446 @default.
• W2121498623 cites W2059226722 @default.
• W2121498623 cites W2066948332 @default.
• W2121498623 cites W2079997831 @default.
• W2121498623 cites W2080546149 @default.
• W2121498623 cites W2084687929 @default.
• W2121498623 cites W2085303804 @default.
• W2121498623 cites W2098367009 @default.
• W2121498623 cites W2115486658 @default.
• W2121498623 cites W2115655561 @default.
• W2121498623 cites W2118690421 @default.
• W2121498623 cites W2121954251 @default.
• W2121498623 cites W2127980806 @default.
• W2121498623 cites W2130449274 @default.
• W2121498623 cites W2135191741 @default.
• W2121498623 cites W2145407244 @default.
• W2121498623 cites W2146269540 @default.
• W2121498623 cites W2148417953 @default.
• W2121498623 cites W2150925403 @default.
• W2121498623 cites W2152174497 @default.
• W2121498623 cites W2164714615 @default.
• W2121498623 cites W21654741 @default.
• W2121498623 cites W2167005644 @default.
• W2121498623 cites W2177920344 @default.
• W2121498623 cites W2178334730 @default.
• W2121498623 cites W2180867946 @default.
• W2121498623 cites W2226417046 @default.
• W2121498623 cites W2227682325 @default.
• W2121498623 cites W2261542984 @default.
• W2121498623 cites W2396561827 @default.
• W2121498623 cites W2397447528 @default.
• W2121498623 cites W2403399240 @default.
• W2121498623 cites W2414082932 @default.
• W2121498623 cites W2415099244 @default.
• W2121498623 cites W2478472187 @default.
• W2121498623 cites W2892580042 @default.
• W2121498623 cites W4240471962 @default.
• W2121498623 cites W9862503 @default.
• W2121498623 cites W650225256 @default.
• W2121498623 doi "https://doi.org/10.1017/s0029665199001202" @default.
• W2121498623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10817157" @default.
• W2121498623 hasPublicationYear "1999" @default.
• W2121498623 type Work @default.
• W2121498623 sameAs 2121498623 @default.
• W2121498623 citedByCount "59" @default.
• W2121498623 countsByYear W21214986232012 @default.
• W2121498623 countsByYear W21214986232013 @default.
• W2121498623 countsByYear W21214986232014 @default.
• W2121498623 countsByYear W21214986232015 @default.
• W2121498623 countsByYear W21214986232016 @default.
• W2121498623 countsByYear W21214986232018 @default.
• W2121498623 countsByYear W21214986232019 @default.
• W2121498623 countsByYear W21214986232021 @default.
• W2121498623 countsByYear W21214986232022 @default.
• W2121498623 crossrefType "journal-article" @default.
• W2121498623 hasAuthorship W2121498623A5015138528 @default.
• W2121498623 hasAuthorship W2121498623A5040925170 @default.
• W2121498623 hasAuthorship W2121498623A5060775202 @default.
• W2121498623 hasAuthorship W2121498623A5084806864 @default.
• W2121498623 hasBestOaLocation W21214986231 @default.
• W2121498623 hasConcept C126322002 @default.
• W2121498623 hasConcept C158846371 @default.
• W2121498623 hasConcept C164705383 @default.
• W2121498623 hasConcept C185592680 @default.
• W2121498623 hasConcept C18903297 @default.
• W2121498623 hasConcept C2777289219 @default.
• W2121498623 hasConcept C2777477808 @default.
• W2121498623 hasConcept C2779959927 @default.

• next