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- W2121504113 abstract "Southern Africa harbors several population groups representing a diversity of gene pool origins. This provides a unique opportunity to study genetic disease predisposition in these populations against a common environmental background. Human leukocyte antigen (HLA) association studies of these populations could improve knowledge on inter-population variation and HLA-related disease susceptibility. The aim of this paper is to review HLA class II disease associations reported for southern African population groups, compare them with findings in other populations and identify those unique to southern Africa. A number of HLA class II disease associations appear to be unique to southern African populations. These include DRB1*14011 association with insulin-dependent diabetes mellitus susceptibility in the Xhosa and DRB1*10 and DQB1*0302 with rheumatoid arthritis susceptibility in the South African (SA) Indian and SA Coloreds, respectively. A noteworthy similarity in class II disease association was observed among southern African Caucasoid and their European parental populations. Unique HLA class II disease associations observed in southern Africa are consistent with the notion that unique environmental and natural selective factors have resulted in certain ethnic-specific HLA class II disease associations, while common HLA class II disease associations found across different populations support the notion that common diseases are caused by common, ancient alleles present in indigenous African populations." @default.
- W2121504113 created "2016-06-24" @default.
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- W2121504113 date "2006-01-26" @default.
- W2121504113 modified "2023-10-10" @default.
- W2121504113 title "HLA class II disease associations in southern Africa" @default.
- W2121504113 cites W1479879849 @default.
- W2121504113 cites W1553821274 @default.
- W2121504113 cites W1607270055 @default.
- W2121504113 cites W1887785635 @default.
- W2121504113 cites W1963688317 @default.
- W2121504113 cites W1966722504 @default.
- W2121504113 cites W1970241693 @default.
- W2121504113 cites W1973094787 @default.
- W2121504113 cites W1974140291 @default.
- W2121504113 cites W1974679766 @default.
- W2121504113 cites W1975087583 @default.
- W2121504113 cites W1975173494 @default.
- W2121504113 cites W1980577967 @default.
- W2121504113 cites W1981661786 @default.
- W2121504113 cites W1984583902 @default.
- W2121504113 cites W1984943195 @default.
- W2121504113 cites W1988714637 @default.
- W2121504113 cites W1990040680 @default.
- W2121504113 cites W1991941671 @default.
- W2121504113 cites W1994197831 @default.
- W2121504113 cites W1999157320 @default.
- W2121504113 cites W1999663661 @default.
- W2121504113 cites W2001724897 @default.
- W2121504113 cites W2007313776 @default.
- W2121504113 cites W2008866279 @default.
- W2121504113 cites W2009149848 @default.
- W2121504113 cites W2012357998 @default.
- W2121504113 cites W2013405032 @default.
- W2121504113 cites W2018625992 @default.
- W2121504113 cites W2019170559 @default.
- W2121504113 cites W2024812424 @default.
- W2121504113 cites W2026664035 @default.
- W2121504113 cites W2029750797 @default.
- W2121504113 cites W2029966123 @default.
- W2121504113 cites W2034092413 @default.
- W2121504113 cites W2036703892 @default.
- W2121504113 cites W2037865470 @default.
- W2121504113 cites W2039237774 @default.
- W2121504113 cites W2045399867 @default.
- W2121504113 cites W2048112155 @default.
- W2121504113 cites W2055966302 @default.
- W2121504113 cites W2057075831 @default.
- W2121504113 cites W2057122918 @default.
- W2121504113 cites W2061356306 @default.
- W2121504113 cites W2063998825 @default.
- W2121504113 cites W2064279157 @default.
- W2121504113 cites W2066135800 @default.
- W2121504113 cites W2073281249 @default.
- W2121504113 cites W2074060790 @default.
- W2121504113 cites W2074280352 @default.
- W2121504113 cites W2075817888 @default.
- W2121504113 cites W2079501979 @default.
- W2121504113 cites W2081903026 @default.
- W2121504113 cites W2084898138 @default.
- W2121504113 cites W2088377390 @default.
- W2121504113 cites W2091122206 @default.
- W2121504113 cites W2091853764 @default.
- W2121504113 cites W2097977705 @default.
- W2121504113 cites W2098290278 @default.
- W2121504113 cites W2102347053 @default.
- W2121504113 cites W2103219211 @default.
- W2121504113 cites W2103938894 @default.
- W2121504113 cites W2104243122 @default.
- W2121504113 cites W2105669755 @default.
- W2121504113 cites W2108590205 @default.
- W2121504113 cites W2116599892 @default.
- W2121504113 cites W2126362207 @default.
- W2121504113 cites W2142354990 @default.
- W2121504113 cites W2146283287 @default.
- W2121504113 cites W2146816378 @default.
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- W2121504113 cites W2171013482 @default.
- W2121504113 cites W2331796918 @default.
- W2121504113 cites W4244025416 @default.
- W2121504113 doi "https://doi.org/10.1111/j.1399-0039.2006.00530.x" @default.
- W2121504113 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16441480" @default.
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