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- W2121566238 abstract "Summary Introduction . It has been generally accepted that female hormones protect against the development of cardiovascular diseases and more especially with regard to the development of degenerative disorders affecting the arteries. Aims . This study attempts to show the relationships between the hormonal component and the artery wall, and evaluates them from a histological and morphometric point of view. Materials and methods . We conducted an experimental study in rats using different groups of animals in order to provide an animal model in which to demonstrate the arterial repercussions of the different hormonal situations. The experimental design was structured in a number of study groups based on hormonal deprivation, followed by replacement that was implemented either pharmacologically or by means of ovarian transplant in the wall of the artery. Results and conclusions . The repercussions of hormone deprivation were not seen very clearly, but detection was possible using morphometric methods. Results show that hormone replacement neutralises the possible degenerative effects stemming from hormone deprivation. We discuss the interaction of estrogenic hormones and their involvement in the development of arterial pathologies, and the evidence that exists in the literature on this issue. [ANGIOLOGIA 2004; 56: 529-38]" @default.
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- W2121566238 date "2004-01-01" @default.
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- W2121566238 title "Estudio de las repercusiones arteriales de la deprivación y aporte de hormonas femeninas. Estudio experimental" @default.
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- W2121566238 doi "https://doi.org/10.1016/s0003-3170(04)74906-8" @default.
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