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• W2121567493 abstract "To see if sodium arsenite enhances the clastogenicity and the mutagenicity of DNA crosslinking agents, Chinese hamster ovary (CHO) cells and human skin fibroblasts were exposed to cis-diamminedichloroplatinum (II) (cis-Pt(II)) or 8-methoxypsoralen (8-MOP) plus long-wave ultraviolet light (UVA) and then to sodium arsenite. The results indicate that the clastogenicity of cis-Pt(II) and 8-MOP plus UVA are enhanced by the post-treatment with sodium arsenite. Chromatid breaks and exchanges are predominantly increased in doubly treated cells. Furthermore, the mutagenicity of cis-Pt(II) at the hypoxanthine-guanine phosphoribosyl transferase locus is also potentiated by sodium arsenite in CHO cells." @default.
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• W2121567493 date "1986-01-01" @default.
• W2121567493 modified "2023-09-24" @default.
• W2121567493 title "Sodium arsenite potentiates the clastogenicity and mutagenicity of dna crosslinking agents" @default.
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• W2121567493 doi "https://doi.org/10.1002/em.2860080111" @default.
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