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- W2121572174 abstract "In a recent report in Trends in Genetics, Gao and Voytas [ 1 Gao X. Voytas D.F. A eukaryotic gene family related to retroelement integrases. Trends Genet. 2005; 21: 133-137 Abstract Full Text Full Text PDF PubMed Scopus (26) Google Scholar ] described a new family of integrase genes that were identified in diverse eukaryotic species, including slime mold, Caenorhabditis elegans, C. briggsae, zebrafish, Takifugu rubripes, Xiphophorus maculates, cow, dog and humans. These genes potentially encode proteins containing ∼400 amino acids with homology to retroviral integrases and transposases, including the integrase-like proteins encoded by Tlr, a family of atypical mobile elements with long terminal inverted repeats (TIRs) from the ciliate Tetrahymena thermophila [ 2 Wells J.M. et al. A small family of elements with long inverted repeats is located near sites of developmentally regulated DNA rearrangement in Tetrahymena thermophila. Mol. Cell Biol. 1994; 14: 5939-5949 Crossref PubMed Scopus (42) Google Scholar , 3 Wuitschick J.D. et al. A novel family of mobile genetic elements is limited to the germline genome in Tetrahymena thermophila. Nucleic Acids Res. 2002; 30: 2524-2537 Crossref PubMed Scopus (78) Google Scholar ]." @default.
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- W2121572174 date "2005-10-01" @default.
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- W2121572174 title "Non-mammalian c-integrases are encoded by giant transposable elements" @default.
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