Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121830841> ?p ?o ?g. }
- W2121830841 endingPage "250" @default.
- W2121830841 startingPage "240" @default.
- W2121830841 abstract "The purpose of this study was to evaluate the effect of a feed additive (OmniGen-AF®, reported to have immune modulating activity) on innate immunity and health events during the periparturient period in dairy heifers when immunity is suppressed. From 60 days prepartum through calving, supplemented heifers (n = 20) received OmniGen-AF® daily and were compared with unsupplemented controls (n = 20). Blood leukocyte innate immune activity (phenotype markers, phagocytic activity, and reactive oxygen species—ROS production) was measured prior to feeding (60 days prepartum), 30 days later, and on days 1, 7, 14, and 30 postpartum. Adverse health events (udder edema, ketosis, displaced abomasum, and death) and milk production were measured at calving and into early lactation. The fraction of leukocytes with measurable CD62L (l-selectin) on their surface from supplemented heifers tended to be greater during the periparturient period in treated heifers than controls (p = 0.100). Likewise, leukocyte phagocytosis of Escherichia coli and Staphylococcus aureus during this time period tended to be greater in heifers supplemented with OmniGen-AF® (p = 0.100). Conversely, ROS production in response to phorbol myristate acetate or when leukocytes were stimulated with killed S. aureus lysate tended to be greater among control heifers compared with supplemented animals (p = 0.100). Supplemented heifers exhibited fewer incidents of udder edema than controls (p = 0.030) and tended to exhibit a lower rate of new cases of mastitis (p = 0.098); however, no differences were observed in milk somatic cell counts or level of milk production. Results demonstrate a positive role of OmniGen-AF® in amplifying leukocyte function consistent with antibacterial activity during the periparturient period, and support the continued study of dietary supplementation to enhance mammary gland health in dairy cows." @default.
- W2121830841 created "2016-06-24" @default.
- W2121830841 creator A5032018819 @default.
- W2121830841 creator A5046547953 @default.
- W2121830841 creator A5047731253 @default.
- W2121830841 creator A5058448649 @default.
- W2121830841 creator A5076789041 @default.
- W2121830841 creator A5086793197 @default.
- W2121830841 creator A5089605581 @default.
- W2121830841 date "2014-10-01" @default.
- W2121830841 modified "2023-09-27" @default.
- W2121830841 title "Modulation of innate immune function and phenotype in bred dairy heifers during the periparturient period induced by feeding an immunostimulant for 60 days prior to delivery" @default.
- W2121830841 cites W1506754512 @default.
- W2121830841 cites W1511204912 @default.
- W2121830841 cites W1548896279 @default.
- W2121830841 cites W165004634 @default.
- W2121830841 cites W1982359099 @default.
- W2121830841 cites W1986679498 @default.
- W2121830841 cites W1987090542 @default.
- W2121830841 cites W1999096587 @default.
- W2121830841 cites W2000696348 @default.
- W2121830841 cites W2017303867 @default.
- W2121830841 cites W2020887676 @default.
- W2121830841 cites W2024915476 @default.
- W2121830841 cites W2034532897 @default.
- W2121830841 cites W2062854303 @default.
- W2121830841 cites W2074028698 @default.
- W2121830841 cites W2077491140 @default.
- W2121830841 cites W2079096224 @default.
- W2121830841 cites W2083251982 @default.
- W2121830841 cites W2087820683 @default.
- W2121830841 cites W2120620359 @default.
- W2121830841 cites W2137211946 @default.
- W2121830841 cites W2152505433 @default.
- W2121830841 cites W2155290476 @default.
- W2121830841 cites W2162667045 @default.
- W2121830841 cites W27333232 @default.
- W2121830841 doi "https://doi.org/10.1016/j.vetimm.2014.08.013" @default.
- W2121830841 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25219783" @default.
- W2121830841 hasPublicationYear "2014" @default.
- W2121830841 type Work @default.
- W2121830841 sameAs 2121830841 @default.
- W2121830841 citedByCount "25" @default.
- W2121830841 countsByYear W21218308412016 @default.
- W2121830841 countsByYear W21218308412017 @default.
- W2121830841 countsByYear W21218308412018 @default.
- W2121830841 countsByYear W21218308412019 @default.
- W2121830841 countsByYear W21218308412020 @default.
- W2121830841 countsByYear W21218308412021 @default.
- W2121830841 countsByYear W21218308412022 @default.
- W2121830841 countsByYear W21218308412023 @default.
- W2121830841 crossrefType "journal-article" @default.
- W2121830841 hasAuthorship W2121830841A5032018819 @default.
- W2121830841 hasAuthorship W2121830841A5046547953 @default.
- W2121830841 hasAuthorship W2121830841A5047731253 @default.
- W2121830841 hasAuthorship W2121830841A5058448649 @default.
- W2121830841 hasAuthorship W2121830841A5076789041 @default.
- W2121830841 hasAuthorship W2121830841A5086793197 @default.
- W2121830841 hasAuthorship W2121830841A5089605581 @default.
- W2121830841 hasConcept C126322002 @default.
- W2121830841 hasConcept C134018914 @default.
- W2121830841 hasConcept C136449434 @default.
- W2121830841 hasConcept C140793950 @default.
- W2121830841 hasConcept C160448771 @default.
- W2121830841 hasConcept C16685009 @default.
- W2121830841 hasConcept C203014093 @default.
- W2121830841 hasConcept C22641795 @default.
- W2121830841 hasConcept C2776344049 @default.
- W2121830841 hasConcept C2776659692 @default.
- W2121830841 hasConcept C2776792119 @default.
- W2121830841 hasConcept C2776921810 @default.
- W2121830841 hasConcept C2776977481 @default.
- W2121830841 hasConcept C2778668663 @default.
- W2121830841 hasConcept C2779234561 @default.
- W2121830841 hasConcept C2779341262 @default.
- W2121830841 hasConcept C54355233 @default.
- W2121830841 hasConcept C71924100 @default.
- W2121830841 hasConcept C86803240 @default.
- W2121830841 hasConcept C8891405 @default.
- W2121830841 hasConcept C89423630 @default.
- W2121830841 hasConceptScore W2121830841C126322002 @default.
- W2121830841 hasConceptScore W2121830841C134018914 @default.
- W2121830841 hasConceptScore W2121830841C136449434 @default.
- W2121830841 hasConceptScore W2121830841C140793950 @default.
- W2121830841 hasConceptScore W2121830841C160448771 @default.
- W2121830841 hasConceptScore W2121830841C16685009 @default.
- W2121830841 hasConceptScore W2121830841C203014093 @default.
- W2121830841 hasConceptScore W2121830841C22641795 @default.
- W2121830841 hasConceptScore W2121830841C2776344049 @default.
- W2121830841 hasConceptScore W2121830841C2776659692 @default.
- W2121830841 hasConceptScore W2121830841C2776792119 @default.
- W2121830841 hasConceptScore W2121830841C2776921810 @default.
- W2121830841 hasConceptScore W2121830841C2776977481 @default.
- W2121830841 hasConceptScore W2121830841C2778668663 @default.
- W2121830841 hasConceptScore W2121830841C2779234561 @default.
- W2121830841 hasConceptScore W2121830841C2779341262 @default.
- W2121830841 hasConceptScore W2121830841C54355233 @default.
- W2121830841 hasConceptScore W2121830841C71924100 @default.