Matches in SemOpenAlex for { <https://semopenalex.org/work/W2121831036> ?p ?o ?g. }
- W2121831036 endingPage "e750" @default.
- W2121831036 startingPage "e745" @default.
- W2121831036 abstract "The aim of this study was to determine by immunohistochemistry the presence and significance of p53 and bcl-2 proteins in oral lichen planus (OLP) and oral squamous cell carcinoma (OSCC).We used 21 cases diagnosed as OLP 16 diagnosed as OSCC and four normal gingival biopsies taken from healthy patients were used as controls. Slides were processed for immunohistochemistry using anti-p53 and anti-bcl-2 monoclonal antibodies.We found p53 immunoexpression in 71.4% OLP cases and 68.7% OSCC cases, with no immunoexpression in control cases. Bcl-2 was negative for all OLP and OSCC cases, and mild positivity was observed in normal tissue. We found significant correlation among p53 expression and OSCC malignancy.Our results suggest that TP53 system mainly promotes a hyperproliferative state by cell cycle arrest of the OLP epithelial cells for repairing damaged DNA nor apoptosis and that anti-apoptotic action of bcl-2 is not important in this disease." @default.
- W2121831036 created "2016-06-24" @default.
- W2121831036 creator A5025142376 @default.
- W2121831036 creator A5031823009 @default.
- W2121831036 creator A5055531151 @default.
- W2121831036 creator A5076245161 @default.
- W2121831036 date "2012-01-01" @default.
- W2121831036 modified "2023-09-26" @default.
- W2121831036 title "P53 and bcl-2 immunoexpression in patients with oral lichen planus and oral squamous cell carcinoma" @default.
- W2121831036 cites W1498586399 @default.
- W2121831036 cites W1863578670 @default.
- W2121831036 cites W186393050 @default.
- W2121831036 cites W1970096001 @default.
- W2121831036 cites W1972441040 @default.
- W2121831036 cites W1975863044 @default.
- W2121831036 cites W1979152565 @default.
- W2121831036 cites W1982211473 @default.
- W2121831036 cites W1989697675 @default.
- W2121831036 cites W2002382793 @default.
- W2121831036 cites W2004074465 @default.
- W2121831036 cites W2046533902 @default.
- W2121831036 cites W2056573152 @default.
- W2121831036 cites W2067311693 @default.
- W2121831036 cites W2069756984 @default.
- W2121831036 cites W2070064660 @default.
- W2121831036 cites W2073188162 @default.
- W2121831036 cites W2077850434 @default.
- W2121831036 cites W2082148036 @default.
- W2121831036 cites W2084164844 @default.
- W2121831036 cites W2085673686 @default.
- W2121831036 cites W2091586771 @default.
- W2121831036 cites W2115497706 @default.
- W2121831036 cites W2118792227 @default.
- W2121831036 cites W2118988630 @default.
- W2121831036 cites W2138531239 @default.
- W2121831036 cites W2186730631 @default.
- W2121831036 cites W2294550615 @default.
- W2121831036 cites W2418149280 @default.
- W2121831036 cites W269205194 @default.
- W2121831036 cites W3147534016 @default.
- W2121831036 cites W43738264 @default.
- W2121831036 doi "https://doi.org/10.4317/medoral.18013" @default.
- W2121831036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3482516" @default.
- W2121831036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22549684" @default.
- W2121831036 hasPublicationYear "2012" @default.
- W2121831036 type Work @default.
- W2121831036 sameAs 2121831036 @default.
- W2121831036 citedByCount "15" @default.
- W2121831036 countsByYear W21218310362013 @default.
- W2121831036 countsByYear W21218310362014 @default.
- W2121831036 countsByYear W21218310362015 @default.
- W2121831036 countsByYear W21218310362016 @default.
- W2121831036 countsByYear W21218310362018 @default.
- W2121831036 countsByYear W21218310362022 @default.
- W2121831036 crossrefType "journal-article" @default.
- W2121831036 hasAuthorship W2121831036A5025142376 @default.
- W2121831036 hasAuthorship W2121831036A5031823009 @default.
- W2121831036 hasAuthorship W2121831036A5055531151 @default.
- W2121831036 hasAuthorship W2121831036A5076245161 @default.
- W2121831036 hasBestOaLocation W21218310361 @default.
- W2121831036 hasConcept C142724271 @default.
- W2121831036 hasConcept C1491633281 @default.
- W2121831036 hasConcept C190283241 @default.
- W2121831036 hasConcept C204232928 @default.
- W2121831036 hasConcept C2776201145 @default.
- W2121831036 hasConcept C2777546739 @default.
- W2121831036 hasConcept C2779399171 @default.
- W2121831036 hasConcept C3017404179 @default.
- W2121831036 hasConcept C3019992690 @default.
- W2121831036 hasConcept C3020813896 @default.
- W2121831036 hasConcept C54355233 @default.
- W2121831036 hasConcept C55493867 @default.
- W2121831036 hasConcept C71924100 @default.
- W2121831036 hasConcept C86803240 @default.
- W2121831036 hasConceptScore W2121831036C142724271 @default.
- W2121831036 hasConceptScore W2121831036C1491633281 @default.
- W2121831036 hasConceptScore W2121831036C190283241 @default.
- W2121831036 hasConceptScore W2121831036C204232928 @default.
- W2121831036 hasConceptScore W2121831036C2776201145 @default.
- W2121831036 hasConceptScore W2121831036C2777546739 @default.
- W2121831036 hasConceptScore W2121831036C2779399171 @default.
- W2121831036 hasConceptScore W2121831036C3017404179 @default.
- W2121831036 hasConceptScore W2121831036C3019992690 @default.
- W2121831036 hasConceptScore W2121831036C3020813896 @default.
- W2121831036 hasConceptScore W2121831036C54355233 @default.
- W2121831036 hasConceptScore W2121831036C55493867 @default.
- W2121831036 hasConceptScore W2121831036C71924100 @default.
- W2121831036 hasConceptScore W2121831036C86803240 @default.
- W2121831036 hasLocation W21218310361 @default.
- W2121831036 hasLocation W21218310362 @default.
- W2121831036 hasLocation W21218310363 @default.
- W2121831036 hasLocation W21218310364 @default.
- W2121831036 hasLocation W21218310365 @default.
- W2121831036 hasOpenAccess W2121831036 @default.
- W2121831036 hasPrimaryLocation W21218310361 @default.
- W2121831036 hasRelatedWork W1999598151 @default.
- W2121831036 hasRelatedWork W2121831036 @default.
- W2121831036 hasRelatedWork W2312371010 @default.