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- W2121837302 abstract "The postprandial lipoprotein metabolism of two orally administered vitamin A-fat loads consisting of either 20% (wt:vol) soybean oil or 17% olive oil plus 3% soybean oil was studied in six normolipidemic young men according to a randomized crossover design. Mean (±SEM) retinyl palmitate concentrations (area under the 24-h curve) were higher in olive oil chylomicrons (97.3 ± 5.5 mmol · L−l · h−l), than in soybean-oil chylomicrons (84.0 ± 10.5 mmol · L−1 · h−1; P < 0.02). Apo-lipoprotein B−48 concentrations were higher in the olive oil chylomicron remnants with densities (d) of 1.006–1.019 compared with soybean-oil remnants. The slower removal of olive oil chy-with soybean-oil remnants. The slower removal of olive oil chylomicron remnants was correlated to hepatic lipase activity (r = 0.84, P < 0.02). The initial HDL-cholesterol concentration (0.87 ±0.17 mmol/L—relatively low but within the normal range for young Dutch men) decreased significantly after ingestion of soybean oil to 0.66 ±0.10 mmol/L after 5 and 7 h, but no significant decrease was observed after olive oil ingestion. Soybean oil induced decreases in HDLs correlated inversely with hepatic lipase (r = −0.88, P < 0.02). The results suggested that competition between olive oil chylomicron remnants and HDL for hepatic lipase may have been the underlying mechanism that prevented the postprandial decrease in HDL cholesterol." @default.
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- W2121837302 date "1993-10-01" @default.
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- W2121837302 title "Different postprandial metabolism of olive oil and soybean oil: a possible mechanism of the high-density lipoprotein conserving effect of olive oil" @default.
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- W2121837302 doi "https://doi.org/10.1093/ajcn/58.4.477" @default.
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