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- W2122013736 abstract "A series of some new 2,5-disubstituted-1,3,4-oxadiazoles 4(a–i) have been conveniently synthesized by intramolecular oxidative cyclization of (E)-2-(arylbenzylidene)-2-[(4-methoxyphenyl)amino]acetohydrazides promoted by iodobenzene diacetate as an oxidant. The structures of the synthesized compounds have been confirmed by 1 H and 13 C NMR, IR, MS, and elemental analysis. All the newly synthesized compounds were screened for their anticonvulsant activity against maximal electroshock (MES) seizure method. Compounds 4g , 4d , and 4a were found to be the most potent of this series. The same compounds showed no neurotoxicity at the maximum dose administered." @default.
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- W2122013736 date "2013-01-01" @default.
- W2122013736 modified "2023-09-26" @default.
- W2122013736 title "Synthesis ofN-[{5-Aryl-1,3,4-oxadiazole-2-yl}methyl]-4-methoxyaniline Derivatives and Their Anticonvulsant Activity" @default.
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- W2122013736 doi "https://doi.org/10.1155/2013/121029" @default.
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