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• W2122034102 abstract "The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3'-terminus of tRNA at one time, using CTP and ATP as substrates. The mystery of CCA-addition without a nucleic acid template by unique RNA polymerases has long fascinated researchers in the field of RNA enzymology. In this review, the mechanisms of RNA polymerization by the remarkable CCA-adding enzyme and its related enzymes are presented, based on their structural features." @default.
• W2122034102 created "2016-06-24" @default.
• W2122034102 creator A5036917638 @default.
• W2122034102 creator A5088238183 @default.
• W2122034102 date "2014-01-01" @default.
• W2122034102 modified "2023-10-04" @default.
• W2122034102 title "Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases" @default.
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• W2122034102 doi "https://doi.org/10.3389/fgene.2014.00036" @default.
• W2122034102 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3925840" @default.
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• W2122034102 hasPublicationYear "2014" @default.
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