FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2122180759> ?p ?o ?g. }

• W2122180759 abstract "Chemotherapy improves the survival of patients with advanced non-small cell lung cancer (NSCLC), but tumor progression is often inevitable. Strategies are needed to improve the therapeutic efficacy of chemotherapy. Over recent years, there has been increasing interest in the role of maintenance therapy after first-line chemotherapy. We investigated the efficacy and safety of standardized allergen-removed Rhus verniciflua Stokes extract (aRVS) as maintenance therapy in patients with non-progressive disease following first-line chemotherapy. We reviewed the medical records of 33 patients with advanced NSCLC, who started treatment with aRVS in a state of tumor regression or stable disease after completion of four or six cycles of induction chemotherapy at the Integrative Cancer Center, Kyung Hee University Hospital at Gangdong from June 2006 to April 2012. The primary objective of this study was progression-free survival (PFS) of aRVS as maintenance therapy. Secondary objectives included assessments of disease control rate (DCR), overall survival (OS), and the safety of aRVS treatment. The median PFS was 5.2 months with a 6- and 12-month PFS rate of 40.6% and 12.9%, respectively. The DCR was 93.9% and the median OS was 34.8 months. The overall survival rates at 12, 24, and 36 months were 84.2%, 76.7% and 49.9%, respectively. We observed no hematologic toxicity, nephrotoxicity, or hepatotoxicity during aRVS treatment. In conclusion, maintenance therapy with aRVS for patients with advanced NSCLC is well-tolerated and offers encouraging improved PFS and OS compared with historical controls. Our data provide further evidence that aRVS may be used beyond disease progression in this clinical setting." @default.
• W2122180759 created "2016-06-24" @default.
• W2122180759 creator A5022481842 @default.
• W2122180759 creator A5039716401 @default.
• W2122180759 creator A5055848254 @default.
• W2122180759 creator A5055974749 @default.
• W2122180759 creator A5056143612 @default.
• W2122180759 creator A5079726966 @default.
• W2122180759 creator A5083003917 @default.
• W2122180759 creator A5087914265 @default.
• W2122180759 date "2013-01-01" @default.
• W2122180759 modified "2023-09-29" @default.
• W2122180759 title "The Efficacy and Safety of Standardized Allergen-Removed Rhus verniciflua Extract as Maintenance Therapy after First-Line Chemotherapy in Patients with Advanced Non-Small Cell Lung Cancer" @default.
• W2122180759 cites W1967405399 @default.
• W2122180759 cites W1982907799 @default.
• W2122180759 cites W1991781559 @default.
• W2122180759 cites W2005244154 @default.
• W2122180759 cites W2008236710 @default.
• W2122180759 cites W2016360463 @default.
• W2122180759 cites W2019680898 @default.
• W2122180759 cites W2037139573 @default.
• W2122180759 cites W2042901938 @default.
• W2122180759 cites W2053017034 @default.
• W2122180759 cites W2066281382 @default.
• W2122180759 cites W2067931817 @default.
• W2122180759 cites W2072271791 @default.
• W2122180759 cites W2077190629 @default.
• W2122180759 cites W2096216990 @default.
• W2122180759 cites W2099725888 @default.
• W2122180759 cites W2100912832 @default.
• W2122180759 cites W2101703456 @default.
• W2122180759 cites W2101711321 @default.
• W2122180759 cites W2112621029 @default.
• W2122180759 cites W2113491100 @default.
• W2122180759 cites W2117266502 @default.
• W2122180759 cites W2122553809 @default.
• W2122180759 cites W2127631797 @default.
• W2122180759 cites W2128082578 @default.
• W2122180759 cites W2130652363 @default.
• W2122180759 cites W2131988196 @default.
• W2122180759 cites W2134667653 @default.
• W2122180759 cites W2136023414 @default.
• W2122180759 cites W2138297714 @default.
• W2122180759 cites W2139248078 @default.
• W2122180759 cites W2139255778 @default.
• W2122180759 cites W2139675556 @default.
• W2122180759 cites W2142247783 @default.
• W2122180759 cites W2144660856 @default.
• W2122180759 cites W2145653040 @default.
• W2122180759 cites W2145835533 @default.
• W2122180759 cites W2149655367 @default.
• W2122180759 cites W2151892458 @default.
• W2122180759 cites W2151914469 @default.
• W2122180759 cites W2153477391 @default.
• W2122180759 cites W2153554788 @default.
• W2122180759 cites W2166058984 @default.
• W2122180759 cites W2168340462 @default.
• W2122180759 cites W2626223149 @default.
• W2122180759 doi "https://doi.org/10.1142/s0192415x13500523" @default.
• W2122180759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23895151" @default.
• W2122180759 hasPublicationYear "2013" @default.
• W2122180759 type Work @default.
• W2122180759 sameAs 2122180759 @default.
• W2122180759 citedByCount "19" @default.
• W2122180759 countsByYear W21221807592014 @default.
• W2122180759 countsByYear W21221807592015 @default.
• W2122180759 countsByYear W21221807592016 @default.
• W2122180759 countsByYear W21221807592017 @default.
• W2122180759 countsByYear W21221807592018 @default.
• W2122180759 countsByYear W21221807592019 @default.
• W2122180759 countsByYear W21221807592020 @default.
• W2122180759 countsByYear W21221807592021 @default.
• W2122180759 countsByYear W21221807592023 @default.
• W2122180759 crossrefType "journal-article" @default.
• W2122180759 hasAuthorship W2122180759A5022481842 @default.
• W2122180759 hasAuthorship W2122180759A5039716401 @default.
• W2122180759 hasAuthorship W2122180759A5055848254 @default.
• W2122180759 hasAuthorship W2122180759A5055974749 @default.
• W2122180759 hasAuthorship W2122180759A5056143612 @default.
• W2122180759 hasAuthorship W2122180759A5079726966 @default.
• W2122180759 hasAuthorship W2122180759A5083003917 @default.
• W2122180759 hasAuthorship W2122180759A5087914265 @default.
• W2122180759 hasConcept C121608353 @default.
• W2122180759 hasConcept C126322002 @default.
• W2122180759 hasConcept C141071460 @default.
• W2122180759 hasConcept C143998085 @default.
• W2122180759 hasConcept C2776256026 @default.
• W2122180759 hasConcept C2776694085 @default.
• W2122180759 hasConcept C2778283404 @default.
• W2122180759 hasConcept C2780739268 @default.
• W2122180759 hasConcept C71924100 @default.
• W2122180759 hasConceptScore W2122180759C121608353 @default.
• W2122180759 hasConceptScore W2122180759C126322002 @default.
• W2122180759 hasConceptScore W2122180759C141071460 @default.
• W2122180759 hasConceptScore W2122180759C143998085 @default.
• W2122180759 hasConceptScore W2122180759C2776256026 @default.
• W2122180759 hasConceptScore W2122180759C2776694085 @default.
• W2122180759 hasConceptScore W2122180759C2778283404 @default.
• W2122180759 hasConceptScore W2122180759C2780739268 @default.
• W2122180759 hasConceptScore W2122180759C71924100 @default.

• next