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• W2122189557 abstract "We have developed a new DNA chip whose substrate has a unique minute columnar array structure made of plastic. The DNA chip exhibits ultrahigh sensitivity, up to 100-fold higher than that of reference DNA chips, which makes it possible to monitor gene expression profiles even with very small amounts of RNA (0.1-0.01 microg of total RNA) without amplification. Differential expression ratios obtained with the new DNA chip were validated against those obtained with quantitative real-time PCR assays. This novel microarray technology would be a powerful tool for monitoring gene expression profiles, especially for clinical diagnosis." @default.
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• W2122189557 date "2006-04-01" @default.
• W2122189557 modified "2023-10-13" @default.
• W2122189557 title "Ultrasensitive DNA Chip: Gene Expression Profile Analysis without RNA Amplification" @default.
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• W2122189557 doi "https://doi.org/10.1093/jb/mvj086" @default.
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