Matches in SemOpenAlex for { <https://semopenalex.org/work/W2122214397> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2122214397 abstract "Enamel matrix derivative Emdogain (EMD) is widely used in periodontal treatment in spite of the fact that its effect on the developing embryo has not been elucidated. The aim of this study was to investigate the teratogenic effect of EMD on the rat embryo neural crest cells. The neural crest is a unique population of cells that migrates from the dorsal neural tube along defined pathways and produces various cell types including the melanocytes, neuronal and glial cells of the sensory, autonomic and enteric nervous system as well as the chromaffin cells of the adrenal gland. These cells have been used extensively for in-vitro studies of neurogenesis. Cultured cells by micromass culture method derived from midbrain of six embryos (13 day postcoitum; 34-36 smites) and exposed to various concentrations of EMD for 5 days at 37°C and differentiated foci were counted. Retinoic Acid (20 μg/mL) was used as standard positive control. These cells were stained using Mayer's hematoxylin which is specific for staining differentiated cell nucleus. Neutral red staining determines cell viability rather than related cell differentiation but is used for normalization of Mayer's hematoxylin results. At the concentration as low as 8 μg/mL of EMD, no toxic effect on fetal cells was observed and it is suggested that EMD has no teratogenic effect at studied concentrations." @default.
- W2122214397 created "2016-06-24" @default.
- W2122214397 creator A5016514960 @default.
- W2122214397 creator A5040228466 @default.
- W2122214397 creator A5053976246 @default.
- W2122214397 creator A5057753900 @default.
- W2122214397 date "2011-01-01" @default.
- W2122214397 modified "2023-10-07" @default.
- W2122214397 title "Evaluation of Enamel Matrix Derivative (EMD) Teratogenicity on the Rat Embryo Neural Crest Culture." @default.
- W2122214397 cites W1535808880 @default.
- W2122214397 cites W1964285345 @default.
- W2122214397 cites W1992571149 @default.
- W2122214397 cites W1994133805 @default.
- W2122214397 cites W1994501339 @default.
- W2122214397 cites W2011881640 @default.
- W2122214397 cites W2013229891 @default.
- W2122214397 cites W2023131959 @default.
- W2122214397 cites W2038309503 @default.
- W2122214397 cites W2039128226 @default.
- W2122214397 cites W2044975611 @default.
- W2122214397 cites W2045375314 @default.
- W2122214397 cites W2048496932 @default.
- W2122214397 cites W2054550175 @default.
- W2122214397 cites W2054778734 @default.
- W2122214397 cites W2056290118 @default.
- W2122214397 cites W2061039485 @default.
- W2122214397 cites W2062525669 @default.
- W2122214397 cites W2067969228 @default.
- W2122214397 cites W2071771559 @default.
- W2122214397 cites W2085578677 @default.
- W2122214397 cites W2091380961 @default.
- W2122214397 cites W2111139543 @default.
- W2122214397 cites W2111674721 @default.
- W2122214397 cites W2122982898 @default.
- W2122214397 cites W2138094668 @default.
- W2122214397 cites W2138819920 @default.
- W2122214397 cites W2142283610 @default.
- W2122214397 cites W2144961968 @default.
- W2122214397 cites W2168540356 @default.
- W2122214397 cites W2283627310 @default.
- W2122214397 cites W2395589951 @default.
- W2122214397 cites W2404700653 @default.
- W2122214397 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3813064" @default.
- W2122214397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24250425" @default.
- W2122214397 hasPublicationYear "2011" @default.
- W2122214397 type Work @default.
- W2122214397 sameAs 2122214397 @default.
- W2122214397 citedByCount "0" @default.
- W2122214397 crossrefType "journal-article" @default.
- W2122214397 hasAuthorship W2122214397A5016514960 @default.
- W2122214397 hasAuthorship W2122214397A5040228466 @default.
- W2122214397 hasAuthorship W2122214397A5053976246 @default.
- W2122214397 hasAuthorship W2122214397A5057753900 @default.
- W2122214397 hasConcept C126749454 @default.
- W2122214397 hasConcept C16685009 @default.
- W2122214397 hasConcept C185592680 @default.
- W2122214397 hasConcept C196843134 @default.
- W2122214397 hasConcept C2780594696 @default.
- W2122214397 hasConcept C2908647359 @default.
- W2122214397 hasConcept C4746552 @default.
- W2122214397 hasConcept C71924100 @default.
- W2122214397 hasConcept C86803240 @default.
- W2122214397 hasConcept C95444343 @default.
- W2122214397 hasConcept C99454951 @default.
- W2122214397 hasConceptScore W2122214397C126749454 @default.
- W2122214397 hasConceptScore W2122214397C16685009 @default.
- W2122214397 hasConceptScore W2122214397C185592680 @default.
- W2122214397 hasConceptScore W2122214397C196843134 @default.
- W2122214397 hasConceptScore W2122214397C2780594696 @default.
- W2122214397 hasConceptScore W2122214397C2908647359 @default.
- W2122214397 hasConceptScore W2122214397C4746552 @default.
- W2122214397 hasConceptScore W2122214397C71924100 @default.
- W2122214397 hasConceptScore W2122214397C86803240 @default.
- W2122214397 hasConceptScore W2122214397C95444343 @default.
- W2122214397 hasConceptScore W2122214397C99454951 @default.
- W2122214397 hasLocation W21222143971 @default.
- W2122214397 hasOpenAccess W2122214397 @default.
- W2122214397 hasPrimaryLocation W21222143971 @default.
- W2122214397 hasRelatedWork W1777892343 @default.
- W2122214397 hasRelatedWork W188401359 @default.
- W2122214397 hasRelatedWork W1988243024 @default.
- W2122214397 hasRelatedWork W2003506496 @default.
- W2122214397 hasRelatedWork W2004294533 @default.
- W2122214397 hasRelatedWork W2033074041 @default.
- W2122214397 hasRelatedWork W2035443199 @default.
- W2122214397 hasRelatedWork W2062213037 @default.
- W2122214397 hasRelatedWork W2069918475 @default.
- W2122214397 hasRelatedWork W2079521227 @default.
- W2122214397 hasRelatedWork W2104450878 @default.
- W2122214397 hasRelatedWork W2331108996 @default.
- W2122214397 hasRelatedWork W2331115603 @default.
- W2122214397 hasRelatedWork W2415240572 @default.
- W2122214397 isParatext "false" @default.
- W2122214397 isRetracted "false" @default.
- W2122214397 magId "2122214397" @default.
- W2122214397 workType "article" @default.